ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Gene Report

Basic Info
Approved Symbol MTHFR
Approved Name methylenetetrahydrofolate reductase (NAD(P)H)
Previous Name "5,10-methylenetetrahydrofolate reductase (NADPH)"
Location 1p36.3
Position chr1:11845780-11866977, -1
External Links HGNC: 7436
Entrez Gene: 4524
Ensembl: ENSG00000177000
UCSC: uc001atc.2
No. of Studies 1 (significant: 0; non-significant: 1; trend: 0)
Source Literature-origin; Mapped by Literature SNP

Gene related studies (count: 1)
Reference Statistical Values/Author Comments Result of Statistical Analysis
Ergul, E., 2012 Thus, the MTHFR gene does not seem to play a role in the etiopathogenesis of ADHD in the cohort studied. Non-significant

Gene related SNPs (count: 11)

Literature-origin SNPs (count: 2)

LD-proxies (count: 9)


Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 12)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 12)


Gene related KEGG pathways (count: 2)

Genes shared at least 5 GO terms with MTHFR (count: 2)

Genes shared at least 2 KEGG pathways with MTHFR (count: 2)

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Region: chr1:11845780..11866977 View in gBrowse
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