ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

SNP Report

Basic Info
Name rs8636 dbSNP Ensembl
Location chr20:10287742(Fwd)
Variant Alleles T/C
Ancestral Allele C
Functional Annotation 3_prime_UTR_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant.
Consequence to Transcript 3_prime_UTR_variant(ENST00000254976; ENST00000304886)
intron_variant(ENST00000421143; ENST00000453544)
nc_transcript_variant(ENST00000421143; ENST00000453544; ENST00000495883)
non_coding_exon_variant(ENST00000495883)
No. of Studies 5 (significant: 2; non-significant: 3; trend: 0)
Source Literature-origin

SNP related studies (count: 5)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Guan L, 2009 single SNP association analyses: Nominal P-value=0.032, Empi...... single SNP association analyses: Nominal P-value=0.032, Empirical P-value=0.491 for ADHD-I More... non-significant for ADHD, but achieve nominal significance f...... non-significant for ADHD, but achieve nominal significance for ADHD-I More... Significant
Sarkar, K., 2012 C/T allelic P-value=0, X2=0.0 for case-control, P-va...... allelic P-value=0, X2=0.0 for case-control, P-value=0.75, X2=0.1 for family-based; genotypic P-value=0.84, X2=0.35 for case-control, P-value=0.77, X2=0.52 for family-based; X2=4.5, TDT P-value=0.03, Relative risk (95% CI)=2.6 (1.4¨C4.9) More... Case-control analysis revealed lack of any significant diffe...... Case-control analysis revealed lack of any significant difference in allelic frequencies between ADHD probands, their parents and controls P>0.05. Family-based analyses showed over transmission of the derived allele 'C' of rs8636 to ADHD probands. More... Significant
Hawi, Z.,2013 T allelic:T=174,NT=149,X2=1.935,P-value=0.1642,EP...... T allelic:T=174,NT=149,X2=1.935,P-value=0.1642,EP-value=0.86,OR=1.18 More... TDT analyses of this SNP showed no significant nominal assoc...... TDT analyses of this SNP showed no significant nominal association with ADHD More... Non-significant
Feng Y, 2005(b) T/C allelic TDT P-value=1, X2=0 in Irvine sample; all...... allelic TDT P-value=1, X2=0 in Irvine sample; allelic TDT P-value=0.875, X2=0.025 in Toronto sample More... there was no significant result both in the Toronto sample a...... there was no significant result both in the Toronto sample and the Irvine sample More... Non-significant
Kim JW, 2007 C/T T Single marker analysis FBAT P-value=0.113; Exploratory analy...... Single marker analysis FBAT P-value=0.113; Exploratory analyses FBAT P-value=0.345 for co-morbid CD, P-value=0.114 for co-morbid MDD, P-value=0.105 for co-morbid BD More... No association was found between ADHD or co-morbidities of A...... No association was found between ADHD or co-morbidities of ADHD and this SNP More... Non-significant

SNP related genes (count: 2)

Literature-origin genes (count: 1)

Genes from other sources Help (count: 1)


SNPs in LD with rs8636 (count: 0) View in gBrowse (chr20:10287742..10287742 )