ADHDgene Database

SNP Report

Basic Info

Name	rs4813925 dbSNP Ensembl
Location	Chr20:10286313(Fwd)
Variant Alleles	A/C
Ancestral Allele	C
Functional Annotation	intron_variant; nc_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000254976; ENST00000421143; ENST00000453544; ENST00000304886; ENST00000495883) nc_transcript_variant(ENST00000453544; ENST00000421143; ENST00000495883)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Guan L, 2009			single SNP association analyses: Nominal P-value=0.043, Empi...... single SNP association analyses: Nominal P-value=0.043, Empirical P-value=0.703 for ADHD-I More...	non-significant for ADHD, but achieve nominal significance f...... non-significant for ADHD, but achieve nominal significance for ADHD-I More...	Significant

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
SNAP25	synaptosomal-associated protein, 25kDa	20p12-p11.2	18(13/5/0)

Approved Symbol	Approved Name	Location
SNAP25-AS1	SNAP25 antisense RNA 1	20p12.2

SNPs in LD with rs4813925 (count: 2) View in gBrowse (chr20:10286313..10287742 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs3746544	3_prime_UTR_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant	13(5/8/0)	1.0[CEU]; 0.915[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.89[MEX]; 1.0[TSI]
rs8636	3_prime_UTR_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant	4(2/2/0)	1.0[ASW]; 1.0[CEU]; 0.915[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 1.0[LWK]; 0.889[MEX]; 0.911[MKK]; 0.974[TSI]; 0.924[YRI]