ADHDgene Database

SNP Report

Basic Info

Name	rs7208257 dbSNP Ensembl
Location	chr17:4620497(Fwd)
Variant Alleles	C/T
Ancestral Allele	T
Functional Annotation	downstream_gene_variant; intron_variant; nc_transcript_variant; NMD_transcript_variant; upstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000570718; ENST00000571791; ENST00000572497; ENST00000572782; ENST00000574888) intron_variant(ENST00000269260; ENST00000346341; ENST00000381488; ENST00000412477; ENST00000570739; ENST00000571206; ENST00000571428; ENST00000572457; ENST00000573886; ENST00000574502; ENST00000574954; ENST00000575131; ENST00000575877; ENST00000576235) nc_transcript_variant(ENST00000570739; ENST00000573886; ENST00000575131) NMD_transcript_variant(ENST00000574502; ENST00000576235) upstream_gene_variant(ENST00000577054)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Brookes K, 2006	A/G		UNPHASED TDT P-value=0.0043; WHAP TDT P-value=0.038 UNPHASED TDT P-value=0.0043; WHAP TDT P-value=0.038	significant association was observed in both UNPHASED and WH...... significant association was observed in both UNPHASED and WHAP analyses More...	Significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
ARRB2	arrestin, beta 2	17p13	1(1/0/0)

SNPs in LD with rs7208257 (count: 4) View in gBrowse (chr17:4577950..4620497 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs931908	intron_variant; nc_transcript_variant; NMD_transcript_variant; upstream_gene_variant	0.904[GIH]
rs9895782	intron_variant; nc_transcript_variant; non_coding_exon_variant; upstream_gene_variant	0.848[CEU]; 0.808[TSI]; 1.0[GIH]
rs9905578	downstream_gene_variant; upstream_gene_variant	0.848[CEU]; 0.808[TSI]; 1.0[GIH]
rs8081507	3_prime_UTR_variant; downstream_gene_variant; nc_transcript_variant; NMD_transcript_variant; non_coding_exon_variant; synonymous_variant; upstream_gene_variant	0.904[GIH]