ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

SNP Report

Basic Info
Name rs6347 dbSNP Ensembl
Location chr5:1411412(Fwd)
Variant Alleles T/C
Ancestral Allele C
Functional Annotation downstream_gene_variant; synonymous_variant.
Consequence to Transcript downstream_gene_variant(ENST00000511750; ENST00000513308)
synonymous_variant(ENST00000270349; ENST00000453492)
No. of Studies 6 (significant: 0; non-significant: 6; trend: 0)
Source Literature-origin

SNP related studies (count: 6)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Friedel S, 2007 A/G A FAMHAP P-value=1 in single marker association analysis FAMHAP P-value=1 in single marker association analysis No association was found with ADHD No association was found with ADHD Non-significant
Brookes K, 2006 A/G UNPHASED TDT P-value=0.391; WHAP TDT P-value=0.106 UNPHASED TDT P-value=0.391; WHAP TDT P-value=0.106 significant association was observed with A allele in WHAP a...... significant association was observed with A allele in WHAP analysis More... Non-significant
Gizer IR, 2009 Meta-analysis model: Random: OR=1.08, 95% CI=0.94-1.22, two-...... Meta-analysis model: Random: OR=1.08, 95% CI=0.94-1.22, two-tailed P-value=0.272; Q-statistic: P-value=0.325, I2=14 More... no evidence to suggest an association between this polymorph...... no evidence to suggest an association between this polymorphisms and ADHD More... Non-significant
Bobb AJ, 2005 allelic TDT P-value=0.17, OR=1.22 in case-control analysis; ...... allelic TDT P-value=0.17, OR=1.22 in case-control analysis; allelic TDT P-value=0.27, RR=0.73 in family-based analysis More... non-significant association non-significant association Non-significant
Genro JP, 2008 A/G P-value=0.86 for total sample; P-value=0.911 for combined sa...... P-value=0.86 for total sample; P-value=0.911 for combined sample More... no allele was significantly more transmitted than expected no allele was significantly more transmitted than expected Non-significant
Feng Y, 2005(a) G/A allelic TDT P-value (2-sided)=0.057, X2=3.612 allelic TDT P-value (2-sided)=0.057, X2=3.612 there was a trend for biased transmission there was a trend for biased transmission Non-significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Genes from other sources Help (count: 0)


SNPs in LD with rs6347 (count: 2) View in gBrowse (chr5:1407116..1411412 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 2)