ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

SNP Report

Basic Info
Name rs40184 dbSNP Ensembl
Location chr5:1395077(Fwd)
Variant Alleles C/T
Ancestral Allele T
Functional Annotation intron_variant.
Consequence to Transcript intron_variant(ENST00000270349; ENST00000453492; ENST00000512002)
No. of Studies 7 (significant: 2; non-significant: 5; trend: 0)
Source Literature-origin

SNP related studies (count: 7)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Genro JP, 2008 A/G P-value=0.878 for total sample; P-value=0.844 for combined s...... P-value=0.878 for total sample; P-value=0.844 for combined sample More... no allele was significantly more transmitted than expected no allele was significantly more transmitted than expected Non-significant
Brookes K, 2006 A/G UNPHASED TDT P-value=0.0045; WHAP TDT P-value=0.004 UNPHASED TDT P-value=0.0045; WHAP TDT P-value=0.004 significant association was observed in both UNPHASED and WH...... significant association was observed in both UNPHASED and WHAP analyses More... Significant
Shang CY, 2011 G/A G allele FBAT P-value=0.639, Z=0.469 for total sample; A all...... G allele FBAT P-value=0.639, Z=0.469 for total sample; A allele FBAT P-value=0.357, Z=0.921 for combined subtype; G allele FBAT P-value=0.081, Z=1.746 for inattentive subtype More... no significant associations in the total sample; displayed a...... no significant associations in the total sample; displayed a trend for association in inattentive subtype More... Non-significant
Doyle C, 2009 T:C TDT P-value=0.56 with T:124 NT:115, OR:1.08 TDT P-value=0.56 with T:124 NT:115, OR:1.08 No statistical significant association was found between thi...... No statistical significant association was found between this marker and ADHD. More... Non-significant
Brookes KJ, 2008(a) C ST1 TDT P-value=0.005, OR=1.26; ST2 TDT P-value=0.31, OR=1.1...... ST1 TDT P-value=0.005, OR=1.26; ST2 TDT P-value=0.31, OR=1.13; ST1&ST2 TDT P-value=0.005, OR=1.2 More... not significantly associated in ST2; nominally significant a...... not significantly associated in ST2; nominally significant associations in the combined analysis of ST1 and ST2 More... Significant
Gizer IR, 2009 Meta-analysis model: Random: OR=1.06, 95% CI=0.90-1.24, P-va...... Meta-analysis model: Random: OR=1.06, 95% CI=0.90-1.24, P-value=0.249; Q-statistic: P-value=0.141, I2=45 More... The Fixed effects meta-analysis indicated a trend towards a ...... The Fixed effects meta-analysis indicated a trend towards a modest association between this allele and ADHD, but random effects meta-analysis yielded a nonsignificant result. Moderate but non-significant heterogeneity in effect sizes across studies was observed. An important caveat to these findings is that the results are based on only 4 studies. More... Non-significant
Nyman ES, 2007 No available information. No available information. No evidence of association was seen. No evidence of association was seen. Non-significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Genes from other sources Help (count: 0)


SNPs in LD with rs40184 (count: 0) View in gBrowse (chr5:1395077..1395077 )