ADHDgene Database

SNP Report

Basic Info

Name	rs3025873 dbSNP Ensembl
Location	Chr20:10269040(Fwd)
Variant Alleles	G/C
Ancestral Allele	C
Functional Annotation	intron_variant; nc_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000421143; ENST00000304886; ENST00000453544; ENST00000254976; ENST00000430336) nc_transcript_variant(ENST00000421143; ENST00000453544)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Kim JW, 2007	G/C	C	Single marker analysis FBAT P-value=1; Exploratory analyses ...... Single marker analysis FBAT P-value=1; Exploratory analyses FBAT P-value=0.723 for co-morbid CD, P-value=0.021 for co-morbid MDD, P-value=0.952 for co-morbid BD More...	Exploratory analysis showed evidence of significant associat...... Exploratory analysis showed evidence of significant association with ADHD and co-morbid MDD More...	Significant

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
SNAP25	synaptosomal-associated protein, 25kDa	20p12-p11.2	18(13/5/0)

Approved Symbol	Approved Name	Location
SNAP25-AS1	SNAP25 antisense RNA 1	20p12.2

SNPs in LD with rs3025873 (count: 16) View in gBrowse (chr20:10247685..10280439 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs2076240	intron_variant; nc_transcript_variant	1(0/1/0)	0.924[CHB]; 1.0[JPT]
rs362998	downstream_gene_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant; synonymous_variant	2(1/1/0)	1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs362585	intron_variant; nc_transcript_variant	1(1/0/0)	0.924[CHB]; 0.959[CHD]; 1.0[JPT]

rs_ID	Functional Annotation	r²[population]
rs2076239	intron_variant; nc_transcript_variant	0.924[CHB]; 1.0[JPT]
rs362995	downstream_gene_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant	0.841[CHB]; 0.874[JPT]
rs2284299	intron_variant; nc_transcript_variant	0.92[CHB]; 1.0[JPT]
rs363004	intron_variant; nc_transcript_variant	1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs362999	intron_variant; nc_transcript_variant	0.833[CHB]; 1.0[JPT]
rs362592	intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CHB]; 0.92[CHD]; 1.0[JPT]
rs362991	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs41378446	intron_variant; nc_transcript_variant	0.828[CHD]
rs362590	intron_variant; nc_transcript_variant	1.0[CHB]; 1.0[JPT]
rs8116632	intron_variant; nc_transcript_variant	0.818[JPT]
rs362582	intron_variant; nc_transcript_variant; upstream_gene_variant	0.924[CHB]; 0.959[CHD]; 1.0[JPT]
rs2284300	intron_variant; nc_transcript_variant	0.924[CHB]; 1.0[CHD]; 1.0[JPT]
rs6133845	intron_variant; nc_transcript_variant	1.0[CHB]; 1.0[JPT]