ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

SNP Report

Basic Info

Name	rs27072 dbSNP Ensembl
Location	Chr5:1394522(Fwd)
Variant Alleles	C/T
Ancestral Allele	C
Functional Annotation	3_prime_UTR_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000453492; ENST00000270349; ENST00000512002)
No. of Studies	7 (significant: 3; non-significant: 4; trend: 0)
Source	Literature-origin

SNP related studies (count: 7)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Feng Y, 2005(a)	G/A		allelic TDT P-value (2-sided)=0.009, X²=6.76 allelic TDT P-value (2-sided)=0.009, X²=6.76	significant evidence for biased transmission of the G allele significant evidence for biased transmission of the G allele	Significant
Gizer IR, 2009			Meta-analysis model: Random: OR=1.2, 95% CI=1.04-1.38, P-val...... Meta-analysis model: Random: OR=1.2, 95% CI=1.04-1.38, P-value=0.006; Q-statistic: P-value=0.217, I²=28 More...	significant but modest association significant but modest association	Significant
Brookes K, 2006	A/G		UNPHASED TDT P-value=0.429; WHAP TDT P-value=0.128 UNPHASED TDT P-value=0.429; WHAP TDT P-value=0.128	possible association was observed with G allele in WHAP anal...... possible association was observed with G allele in WHAP analysis More...	Non-significant
Ouellet-Morin I, 2008	G/A		QTDT P-value=0.007 in AT model, P-value=0.039 in AO model at...... QTDT P-value=0.007 in AT model, P-value=0.039 in AO model at 6 years old, P-value=0.053 in AT model at 7 years old; P-value=0.021, P-value=0.018 in AT model at 6 and 7 years old for ADHD symptoms; P-value=0.009 in AT model for hyperactivity/impulsivity, P-value=0.02 in AT model for inattention at 6 years old More...	a significant association was found with symptoms of inatten...... a significant association was found with symptoms of inattention and hyperactivity/impulsivity More...	Significant
Friedel S, 2007	C/T	C	FAMHAP P-value=0.85 in single marker association analysis FAMHAP P-value=0.85 in single marker association analysis	No association was found with ADHD No association was found with ADHD	Non-significant
Genro JP, 2008	C/T		P-value=0.305 for total sample; P-value=0.563 for combined s...... P-value=0.305 for total sample; P-value=0.563 for combined sample More...	no allele was significantly more transmitted than expected no allele was significantly more transmitted than expected	Non-significant
Shang CY, 2011	C/T		T allele FBAT P-value=0.586, Z=0.544 for total sample; T all...... T allele FBAT P-value=0.586, Z=0.544 for total sample; T allele FBAT P-value=0.227, Z=1.209 for combined subtype; C allele FBAT P-value=0.718, Z=0.361 for inattentive subtype More...	no significant associations in the total sample no significant associations in the total sample	Non-significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Genes from other sources (count: 0)

SNPs in LD with rs27072 (count: 0) View in gBrowse (chr5:1394522..1394522 )