ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

SNP Report

Basic Info
Name rs27072 dbSNP Ensembl
Location chr5:1394522(Fwd)
Variant Alleles C/T
Ancestral Allele C
Functional Annotation 3_prime_UTR_variant.
Consequence to Transcript 3_prime_UTR_variant(ENST00000270349; ENST00000453492; ENST00000512002)
No. of Studies 7 (significant: 3; non-significant: 4; trend: 0)
Source Literature-origin

SNP related studies (count: 7)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Ouellet-Morin I, 2008 G/A QTDT P-value=0.007 in AT model, P-value=0.039 in AO model at...... QTDT P-value=0.007 in AT model, P-value=0.039 in AO model at 6 years old, P-value=0.053 in AT model at 7 years old; P-value=0.021, P-value=0.018 in AT model at 6 and 7 years old for ADHD symptoms; P-value=0.009 in AT model for hyperactivity/impulsivity, P-value=0.02 in AT model for inattention at 6 years old More... a significant association was found with symptoms of inatten...... a significant association was found with symptoms of inattention and hyperactivity/impulsivity More... Significant
Genro JP, 2008 C/T P-value=0.305 for total sample; P-value=0.563 for combined s...... P-value=0.305 for total sample; P-value=0.563 for combined sample More... no allele was significantly more transmitted than expected no allele was significantly more transmitted than expected Non-significant
Shang CY, 2011 C/T T allele FBAT P-value=0.586, Z=0.544 for total sample; T all...... T allele FBAT P-value=0.586, Z=0.544 for total sample; T allele FBAT P-value=0.227, Z=1.209 for combined subtype; C allele FBAT P-value=0.718, Z=0.361 for inattentive subtype More... no significant associations in the total sample no significant associations in the total sample Non-significant
Brookes K, 2006 A/G UNPHASED TDT P-value=0.429; WHAP TDT P-value=0.128 UNPHASED TDT P-value=0.429; WHAP TDT P-value=0.128 possible association was observed with G allele in WHAP anal...... possible association was observed with G allele in WHAP analysis More... Non-significant
Gizer IR, 2009 Meta-analysis model: Random: OR=1.2, 95% CI=1.04-1.38, P-val...... Meta-analysis model: Random: OR=1.2, 95% CI=1.04-1.38, P-value=0.006; Q-statistic: P-value=0.217, I2=28 More... significant but modest association significant but modest association Significant
Feng Y, 2005(a) G/A allelic TDT P-value (2-sided)=0.009, X2=6.76 allelic TDT P-value (2-sided)=0.009, X2=6.76 significant evidence for biased transmission of the G allele significant evidence for biased transmission of the G allele Significant
Friedel S, 2007 C/T C FAMHAP P-value=0.85 in single marker association analysis FAMHAP P-value=0.85 in single marker association analysis No association was found with ADHD No association was found with ADHD Non-significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Genes from other sources Help (count: 0)


SNPs in LD with rs27072 (count: 0) View in gBrowse (chr5:1394522..1394522 )