Hot Results
- Quick Search
- Large-scale studies
- Genome-wide Association Studies of ADHD
- Genome-wide Linkage Studies of ADHD
- Genome-wide CNV Analyses of ADHD
- Meta-analysis Studies of ADHD
- Data Summary
KEGG Pathway Report
Basic Info
| ID | hsa03060 |
|---|---|
| Name | Protein export |
| Description | The protein export is the active transport of proteins from the cytoplasm to the exterior of the cell, or to the periplasmic compartment in Gram-negative bacteria. The sec dependent pathway is the general protein export system that transports newly synthesized proteins into or across the cell membrane. The translocation channel is formed from a conserved trimeric membrane protein complex, called the Sec61/SecY complex. The twin-arginine translocation (Tat) pathway is another protein transport system that transports folded proteins in bacteria, archaea, and chloroplasts. Many Tat systems comprise three functionally different membrane proteins, TatA, TatB, and TatC, but TatA and TatE seem to have overlapping functions, with TatA having by far the more important role. |
| No. of Genes in ADHDgene | 7 |
| Source | Pathway by Database Search |
Pathway related genes in ADHDgene (count: 7)
Literature-origin genes (count: 0)
Genes from other sources 
(count: 7)
| Approved Symbol | Approved Name | Location | Source |
|---|---|---|---|
| SRPR | signal recognition particle receptor (docking protein) | 11q24-q25 | Mapped by significant region |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 9q33.3 | Mapped by significant region |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 7q31 | Mapped by CNV |
| SPCS2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | 11q13.4 | Mapped by significant region |
| SEC11C | SEC11 homolog C (S. cerevisiae) | 18q21.32 | Mapped by significant region |
| SRP19 | signal recognition particle 19kDa | 5q21-q22 | Mapped by LD-proxy |
| SEC61B | Sec61 beta subunit | 9q22.32-q31.3 | Mapped by significant region |