ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

KEGG Pathway Report

Basic Info

ID	hsa05120
Name	Epithelial cell signaling in Helicobacter pylori infection
Description	Two major virulence factors of H. pylori are the vacuolating cytotoxin (VacA) and the cag type-IV secretion system (T4SS) and its translocated effector protein, cytotoxin-associated antigen A (CagA).
No. of Genes in ADHDgene	16
Source	Pathway by Database Search

Pathway related genes in ADHDgene (count: 16)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
GIT1	G protein-coupled receptor kinase interacting ArfGAP 1	17p11.2	2(1/1/0)

Genes from other sources (count: 15)

Approved Symbol	Approved Name	Location	Source
MAPK9	mitogen-activated protein kinase 9	5q35	Mapped by CNV
ATP6V1C2	ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2	2p25.1	Mapped by significant region
CXCR2	chemokine (C-X-C motif) receptor 2	2q35	Mapped by significant region
CXCR1	chemokine (C-X-C motif) receptor 1	2q35	Mapped by significant region
PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	11q13-q14	Mapped by significant region
ADAM17	ADAM metallopeptidase domain 17	2p25	Mapped by significant region
ATP6V1G1	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1	9q33.1	Mapped by significant region
ATP6V1F	ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F	7q32.1	Mapped by LD-proxy
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	11q13	Mapped by significant region
JAM3	junctional adhesion molecule 3	11q25	Mapped by significant region
TJP1	tight junction protein 1 (zona occludens 1)	15q13	Mapped by CNV; Mapped by significant region
TCIRG1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3	11q13.2	Mapped by significant region
PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	16q24.1	Mapped by significant region
ATP6V0A2	ATPase, H+ transporting, lysosomal V0 subunit a2	12q24.31	Mapped by CNV
ATP6V0D2	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2	8q21.3	Mapped by CNV