ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

GO Report

Basic Info

ID	GO:0005834
Name	heterotrimeric G-protein complex
Type	Cellular Component
No. of Genes in ADHDgene	7
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 7)

Literature-origin genes (count: 5)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
GNAZ	guanine nucleotide binding protein (G protein), alpha z polypeptide	22q11.1-q11.2	1(0/1/0)
GNAL	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type	18p11.22-p11.21	1(1/0/0)
GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	16q13	1(0/1/0)
GNAT2	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2	1p13	1(1/0/0)	NAS[1936270]
ARRB1	arrestin, beta 1	11q13	2(1/1/0)	TAS[10823817]

Genes from other sources (count: 2)

Approved Symbol	Approved Name	Source	Evidence[PMID]
GNG10	guanine nucleotide binding protein (G protein), gamma 10	Mapped by significant region
GNG3	guanine nucleotide binding protein (G protein), gamma 3	Mapped by significant region