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- Data Summary
GO Report
Basic Info
| ID | GO:0043197 |
|---|---|
| Name | dendritic spine |
| Type | Cellular Component |
| No. of Genes in ADHDgene | 12 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 12)
Literature-origin genes (count: 5)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| DRD4 | dopamine receptor D4 | 11p15.5 | 67(49/18/0) | |
| MAP1B | microtubule-associated protein 1B | 5q13 | 1(0/0/1) | |
| GSK3B | glycogen synthase kinase 3 beta | 3q13.3 | 1(1/0/0) | |
| GRID2 | glutamate receptor, ionotropic, delta 2 | 4q22 | 1(0/0/1) | |
| NOS1 | nitric oxide synthase 1 (neuronal) | 12q14-qter | 1(1/0/0) |
Genes from other sources (count: 7)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | Mapped by significant region | |
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | Mapped by significant region | |
| CANX | calnexin | Mapped by CNV | |
| LPAR1 | lysophosphatidic acid receptor 1 | Mapped by significant region | |
| CNIH2 | cornichon homolog 2 (Drosophila) | Mapped by significant region | |
| P2RX3 | purinergic receptor P2X, ligand-gated ion channel, 3 | Mapped by significant region | |
| MTMR2 | myotubularin related protein 2 | Mapped by significant region |