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- Genome-wide Association Studies of ADHD
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- Data Summary
GO Report
Basic Info
| ID | GO:0000186 |
|---|---|
| Name | activation of MAPKK activity |
| Type | Biological Process |
| No. of Genes in ADHDgene | 9 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 9)
Literature-origin genes (count: 2)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| NGF | nerve growth factor (beta polypeptide) | 1p13.1 | 2(2/0/0) | |
| GRM1 | glutamate receptor, metabotropic 1 | 6q24 | 1(1/0/0) |
Genes from other sources (count: 7)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| TAOK2 | TAO kinase 2 | Mapped by CNV | IDA[10660600] |
| MAPK1 | mitogen-activated protein kinase 1 | Mapped by LD-proxy | |
| TGFBR1 | transforming growth factor, beta receptor 1 | Mapped by significant region | IDA[18625725] |
| MAPK3 | mitogen-activated protein kinase 3 | Mapped by CNV | |
| KIDINS220 | kinase D-interacting substrate, 220kDa | Mapped by significant region | |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | Mapped by LD-proxy; Mapped by significant region | IDA[11959862] |
| GADD45G | growth arrest and DNA-damage-inducible, gamma | Mapped by significant region |