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- Data Summary
GO Report
Basic Info
| ID | GO:0005089 |
|---|---|
| Name | Rho guanyl-nucleotide exchange factor activity |
| Type | Molecular Function |
| No. of Genes in ADHDgene | 11 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 11)
Literature-origin genes (count: 4)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| TRIO | triple functional domain (PTPRF interacting) | 5p14-p15.1 | 1(0/0/1) | |
| NET1 | neuroepithelial cell transforming 1 | 10p15 | 0 | |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 6q25 | 1(0/0/1) | |
| DOCK10 | dedicator of cytokinesis 10 | 2q36.3 | 1(0/0/1) |
Genes from other sources (count: 7)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | Mapped by CNV; Mapped by significant region | |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | Mapped by PBA pathway | |
| MCF2L | MCF.2 cell line derived transforming sequence-like | Mapped by CNV | |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | Mapped by PBA pathway | IDA[9857026] |
| FGD3 | FYVE, RhoGEF and PH domain containing 3 | Mapped by significant region | |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | Mapped by significant region | |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 | Mapped by significant region |