ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0001077
Name RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
Type molecular function
No. of Genes in ADHDgene  8
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 8)

Literature-origin genes (count: 2)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 6p12 1(1/0/0) IEA
CREB5 cAMP responsive element binding protein 5 7p15 1(0/0/1) IEA

Genes from other sources Help (count: 6)

Approved Symbol Approved Name Source Evidence[PMID]
GLIS2 GLIS family zinc finger 2 Mapped by significant region ISS
KLF4 Kruppel-like factor 4 (gut) Mapped by significant region IMP
RBPJ recombination signal binding protein for immunoglobulin kappa J region Mapped by CNV IDA[18663143]
FOXC2 forkhead box C2 (MFH-1, mesenchyme forkhead 1) Mapped by significant region IDA
STK16 serine/threonine kinase 16 Mapped by significant region IEA
TCF21 transcription factor 21 Mapped by CNV; Mapped by significant region ISS