ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0043197
Name dendritic spine
Type cellular component
No. of Genes in ADHDgene  12
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 12)

Literature-origin genes (count: 5)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
NOS1 nitric oxide synthase 1 (neuronal) 12q24.22 1(1/0/0) IEA
MAP1B microtubule-associated protein 1B 5q13 1(0/0/1) IEA
GRID2 glutamate receptor, ionotropic, delta 2 4q22 1(0/0/1) ISS
GSK3B glycogen synthase kinase 3 beta 3q13.3 1(1/0/0) IEA
DRD4 dopamine receptor D4 11p15.5 67(49/18/0) IEA

Genes from other sources Help (count: 7)

Approved Symbol Approved Name Source Evidence[PMID]
P2RX3 purinergic receptor P2X, ligand-gated ion channel, 3 Mapped by significant region IEA
CNIH2 cornichon family AMPA receptor auxiliary protein 2 Mapped by significant region ISS
CANX calnexin Mapped by CNV IEA
MTMR2 myotubularin related protein 2 Mapped by significant region ISS
SHANK2 SH3 and multiple ankyrin repeat domains 2 Mapped by significant region ISS
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme Mapped by significant region IEA
LPAR1 lysophosphatidic acid receptor 1 Mapped by significant region IEA