Hot Results
- Quick Search
- Large-scale studies
- Genome-wide Association Studies of ADHD
- Genome-wide Linkage Studies of ADHD
- Genome-wide CNV Analyses of ADHD
- Meta-analysis Studies of ADHD
- Data Summary
GO Report
Basic Info
| ID | GO:0007271 |
|---|---|
| Name | synaptic transmission, cholinergic |
| Type | Biological Process |
| No. of Genes in ADHDgene | 8 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 8)
Literature-origin genes (count: 3)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| CHRNA4 | cholinergic receptor, nicotinic, alpha 4 | 20 | 7(4/3/0) | |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 | 15q24 | 1(0/1/0) | |
| SLC5A7 | solute carrier family 5 (choline transporter), member 7 | 2q12 | 1(1/0/0) |
Genes from other sources (count: 5)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| RAPSN | receptor-associated protein of the synapse | Mapped by LD-proxy | IGI[18420419] |
| CHRNB4 | cholinergic receptor, nicotinic, beta 4 | Mapped by LD-proxy | TAS[1330682] |
| BCHE | butyrylcholinesterase | Mapped by CNV | |
| ADORA2A | adenosine A2a receptor | Mapped by CNV | |
| ACHE | acetylcholinesterase | Mapped by PBA pathway |