ADHDgene Database

Gene Report

Basic Info

Approved Symbol	RAX
Symbol Alias	RX
Approved Name	retina and anterior neural fold homeobox
Location	18q21.31
Position	chr18:56934267-56941318, -1
External Links	HGNC: 18662 Entrez Gene: 30062 Ensembl: ENSG00000134438 UCSC: uc002lhx.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by LD-proxy; Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 2)

rs_ID	Location	Functional Annotation
rs17769086	chr18:56945838(Fwd)	intron_variant; upstream_gene_variant
rs9965777	chr18:56945392(Fwd)	intron_variant; upstream_gene_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
18q21.31-21.32	chr18:53800000-59000000	1 (1/0/0)

Gene related GO terms (count: 9)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0007601	visual perception	biological process	TAS[10625658]	29
GO:0003700	sequence-specific DNA binding transcription factor activity	molecular function	IEA	148
GO:0005634	nucleus	cellular component	IEA	877
GO:0043010	camera-type eye development	biological process	IEA	6
GO:0021854	hypothalamus development	biological process	IEA	2
GO:0006351	transcription, DNA-dependent	biological process	IEA	281
GO:0043565	sequence-specific DNA binding	molecular function	IEA	80
GO:0007389	pattern specification process	biological process	IEA	13
GO:0060173	limb development	biological process	IEA	1

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with RAX (count: 4)

Gene Symbol	Pathway Count	Pathway List
HOXB1	5	sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent; sequence-specific DNA binding; pattern specification process;
TBX1	5	sequence-specific DNA binding transcription factor activity; nucleus; transcription, DNA-dependent; sequence-specific DNA binding; pattern specification process;
ETS1	5	sequence-specific DNA binding transcription factor activity; nucleus; hypothalamus development; transcription, DNA-dependent; sequence-specific DNA binding;
FOXL1	5	sequence-specific DNA binding transcription factor activity; nucleus; camera-type eye development; sequence-specific DNA binding; pattern specification process;

Genes shared at least 2 KEGG pathways with RAX (count: 0)

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Region: chr18:56934267..56941318 View in gBrowse