Ribases, M., 201222404661
||Ribases M., Ramos-Quiroga J. A., Hervas A., Sanchez-Mora C., Bosch R., Bielsa A., Gastaminza X., Lesch K. P., Reif A., Renner T. J., Romanos M., Warnke A., Walitza S., Freitag C., Meyer J., Palmason H., Casas M., Bayes M. and Cormand B. (2012) "Candidate system analysis in ADHD: evaluation of nine genes involved in dopaminergic neurotransmission identifies association with DRD1." World J Biol Psychiatry, 13(4): 281-92.
||case-control and family-based
||Candidate-gene association study
||Discovery cohort: Childhood ADHD sample: 322 children with ADHD and 322 sex-matched unrelated controls. 196 affected children and their parents were used for the subsequent family-based study. Discovery cohort: Adulthood ADHD sample: 211 ADHD subjects and 211 sex-matched unrelated controls. Replication cohort: 353 nuclear ADHD families from Germany
||German an Spanish
||Discovery cohort: Childhood ADHD sample: Seventy-nine percent of patients and controls were male. Discovery cohort: Adulthood ADHD sample: Seventy-three percent of subjects were male. Replication cohort: Eighty-two percent of probands were males.
Children/Adolescents and Adults
Discovery cohort: Childhood ADHD sample: The average age at assessment was 9.3 years (SD=2.6) for patients and 36.8 years (SD=17.0) for controls. For the subsequent family-based study, the average age at assessment was 9.1 years (SD=2.8) for probands and 43 years (SD=7.9) for parents. Discovery cohort: Adulthood ADHD sample: The average age at diagnosis was 29.8 years (SD=12.1) for patients and 44.2 years (SD=14.7) for controls. Replication cohort: The average age at assessment was 10.74 years (SD=2.47) for probands.
SNPs reported by this study (count: 5)
Genes reported by this study (count: 2)