ADHDgene Database

SNP Report

Basic Info

Name	rs6454674 dbSNP Ensembl
Location	Chr6:88872930(Fwd)
Variant Alleles	T/G
Ancestral Allele	G
Functional Annotation	intron_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000551417; ENST00000369501; ENST00000535130; ENST00000369499) upstream_gene_variant(ENST00000428600)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Lu AT, 2008	G/T		P-value>0.05 P-value>0.05	showed no association with ADHD showed no association with ADHD	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
CNR1	cannabinoid receptor 1 (brain)	6q14-q15	1(1/0/0)

SNPs in LD with rs6454674 (count: 2) View in gBrowse (chr6:88865901..88872930 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs806381	intron_variant	1.0[CEU]; 0.904[CHB]; 0.937[JPT]
rs6454673	intron_variant	0.86[CEU]; 0.873[JPT]; 0.951[YRI]