ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs6279 dbSNP Ensembl
Location	Chr11:113281073(Fwd)
Variant Alleles	G/C
Ancestral Allele	G
Functional Annotation	3_prime_UTR_variant; downstream_gene_variant; intron_variant; nc_transcript_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000346454; ENST00000544518; ENST00000362072; ENST00000355319; ENST00000542968) downstream_gene_variant(ENST00000538967; ENST00000540600; ENST00000535984; ENST00000539420) intron_variant(ENST00000546284) nc_transcript_variant(ENST00000546284)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Nyman ES, 2007			No available information. No available information.	No evidence of association was seen. No evidence of association was seen.	Non-significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
DRD2	dopamine receptor D2	11q22-q23	10(3/7/0)

Genes from other sources (count: 0)

SNPs in LD with rs6279 (count: 26) View in gBrowse (chr11:113252147..113307129 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 2)

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs6275	downstream_gene_variant; synonymous_variant	2(0/2/0)	1.0[CEU]; 0.954[CHB]; 1.0[JPT]; 1.0[YRI]
rs1800497	downstream_gene_variant; missense_variant	2(2/0/0)	0.83[CHB]

LD-proxies (count: 24)

rs_ID	Functional Annotation	r²[population]
rs2587550	downstream_gene_variant; upstream_gene_variant	0.957[CEU]; 1.0[CHB]; 1.0[JPT]
rs4590907	intron_variant; upstream_gene_variant	0.826[JPT]
rs4586205	intron_variant; nc_transcript_variant	0.866[JPT]
rs11214598	NMD_transcript_variant; intron_variant	0.877[CEU]; 0.954[CHB]; 0.953[JPT]
rs2242592	downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs2245805	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.954[CHB]; 0.861[JPT]
rs2242591	downstream_gene_variant; intron_variant; nc_transcript_variant	0.823[CHB]; 0.945[JPT]
rs6276	3_prime_UTR_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.957[CEU]; 1.0[CHB]; 1.0[JPT]
rs10891541	intron_variant	0.867[JPT]
rs2002453	intron_variant; nc_transcript_variant; upstream_gene_variant	0.954[CHB]; 0.861[JPT]
rs10891545	downstream_gene_variant; upstream_gene_variant	0.826[JPT]
rs6278	3_prime_UTR_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.83[CHB]
rs4938016	downstream_gene_variant; missense_variant	0.957[CEU]; 0.955[CHB]; 0.955[JPT]
rs1124492	downstream_gene_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant	0.867[JPT]
rs1124493	downstream_gene_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs12224538	intron_variant; upstream_gene_variant	0.834[JPT]
rs2734842	downstream_gene_variant; intron_variant; nc_transcript_variant	0.954[CEU]; 0.956[CHB]; 1.0[JPT]
rs1003641	downstream_gene_variant; upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs4938014	NMD_transcript_variant; intron_variant	0.826[JPT]
rs11214602	downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CHB]; 1.0[JPT]
rs2734841	downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs2005313	intron_variant; nc_transcript_variant; upstream_gene_variant	0.954[CHB]; 0.866[JPT]
rs2859545	downstream_gene_variant; upstream_gene_variant	0.954[CEU]; 1.0[CHB]; 1.0[JPT]
rs1076562	intron_variant; nc_transcript_variant; upstream_gene_variant	0.954[CHB]; 0.861[JPT]