ADHDgene Database

SNP Report

Basic Info

Name	rs2873804 dbSNP Ensembl
Location	Chr9:136505644(Fwd)
Variant Alleles	T/C
Ancestral Allele	C
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000263611; ENST00000393056)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Guan L, 2009			single SNP association analyses: Nominal P-value=0.05, Empir...... single SNP association analyses: Nominal P-value=0.05, Empirical P-value=0.566 for ADHD-I More...	non-significant for ADHD, but achieve nominal significance f...... non-significant for ADHD, but achieve nominal significance for ADHD-I More...	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
DBH	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	9q34	20(11/9/0)

SNPs in LD with rs2873804 (count: 11) View in gBrowse (chr9:136498761..136511385 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs1548364	intron_variant	2(0/2/0)	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs5320	missense_variant	1(1/0/0)	0.817[CHD]; 1.0[JPT]
rs1108581	intron_variant	1(0/1/0)	1.0[CHB]; 1.0[CHD]; 0.915[JPT]
rs1611125	downstream_gene_variant; intron_variant	1(0/1/0)	0.828[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 0.873[GIH]; 1.0[JPT]; 1.0[MEX]; 0.832[MKK]; 0.978[TSI]
rs1108580	intron_variant; splice_region_variant; synonymous_variant	5(1/4/0)	0.92[CEU]; 0.877[CHD]; 0.859[GIH]; 0.824[JPT]; 0.926[LWK]; 0.913[MEX]; 0.883[MKK]; 0.955[TSI]
rs1076150	upstream_gene_variant	1(1/0/0)	0.871[MEX]; 0.867[TSI]

rs_ID	Functional Annotation	r²[population]
rs1611123	downstream_gene_variant; intron_variant	0.817[CHD]; 0.924[GIH]; 1.0[JPT]; 0.831[MEX]; 0.869[TSI]
rs1611122	downstream_gene_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs1611120	intron_variant	0.817[CHD]; 1.0[JPT]
rs1541333	downstream_gene_variant; intron_variant	0.882[CEU]
rs3025388	intron_variant	1.0[CHB]; 1.0[CHD]; 0.824[JPT]