ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

SNP Report

Basic Info

Name	rs2652511 dbSNP Ensembl
Location	Chr5:1446389(Fwd)
Variant Alleles	A/G
Ancestral Allele	G
Functional Annotation	upstream_gene_variant.
Consequence to Transcript	upstream_gene_variant(ENST00000453492; ENST00000513308; ENST00000270349)
No. of Studies	5 (significant: 3; non-significant: 1; trend: 1)
Source	Literature-origin

SNP related studies (count: 5)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Brookes K, 2006	A/G		UNPHASED TDT P-value=0.0182; WHAP TDT P-value=0.120 UNPHASED TDT P-value=0.0182; WHAP TDT P-value=0.120	significant association was observed in UNPHASED analysis significant association was observed in UNPHASED analysis	Significant
Xu X, 2009(b)	C/T		TDT: P-value=0.919 in UK sample; P-value=0.123 in Taiwanese ...... TDT: P-value=0.919 in UK sample; P-value=0.123 in Taiwanese sample; P-value=0315 in combined sample. More...	no significant association with ADHD was found no significant association with ADHD was found	Non-significant
Genro JP, 2007	C/T		Allelic test P-value=0.03 in the total sample, P-value=0.004...... Allelic test P-value=0.03 in the total sample, P-value=0.004 in combined type sample, TDT analysis P-value=0.13 in the total sample, P-value=0.03 in combined type sample More...	A significant association for biased transmission of the C a...... A significant association for biased transmission of the C allele at the -839 C>T polymorphism to ADHD children in the total sample was observed, which was strengthened when the analyses were restricted to the combined type only. Biased transmission of the C allele for the combined subtype was also observed in the TDT analyses, More...	Significant
Genro JP, 2008	C/T		P-value=0.153 for total sample; P-value=0.026 for combined s...... P-value=0.153 for total sample; P-value=0.026 for combined sample More...	showed biased transmission for ADHD children in the DSM-IV c...... showed biased transmission for ADHD children in the DSM-IV combined subtype More...	Significant
Langley K, 2005	C/T			polymorphism found through mutational analysis that has prev...... polymorphism found through mutational analysis that has previously been reported [Rubie et al., 2001] More...	Trend

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Genes from other sources (count: 0)

SNPs in LD with rs2652511 (count: 0) View in gBrowse (chr5:1446389..1446389 )