ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

SNP Report

Basic Info
Name rs1889189 dbSNP Ensembl
Location chr20:10197086(Fwd)
Variant Alleles T/C
Ancestral Allele C
Functional Annotation intron_variant; nc_transcript_variant; upstream_gene_variant.
Consequence to Transcript intron_variant(ENST00000421143; ENST00000426491; ENST00000451151; ENST00000453544; ENST00000603542; ENST00000605592)
nc_transcript_variant(ENST00000421143; ENST00000426491; ENST00000451151; ENST00000453544; ENST00000603542; ENST00000605592)
upstream_gene_variant(ENST00000254976; ENST00000304886; ENST00000430336)
No. of Studies 3 (significant: 0; non-significant: 3; trend: 0)
Source Literature-origin

SNP related studies (count: 3)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Feng Y, 2005(b) T/C allelic TDT P-value=0.508, X2=0.439 in Irvine sam...... allelic TDT P-value=0.508, X2=0.439 in Irvine sample; allelic TDT P-value=0.084, X2=2.988 in Toronto sample More... there was no significant result both in the Toronto sample a...... there was no significant result both in the Toronto sample and the Irvine sample More... Non-significant
Sarkar, K., 2012 C/T allelic P-value=0.47, X2=0.52 for case-control, P...... allelic P-value=0.47, X2=0.52 for case-control, P-value=0.39, X2=0.75 for family-based; genotypic P-value=0.29, X2=2.47 for case-control, P-value=0.13, X2=4.13 for family-based More... Case-control analysis revealed lack of any significant diffe...... Case-control analysis revealed lack of any significant difference in allelic frequencies between ADHD probands, their parents and controls P>0.05. More... Non-significant
Brookes K, 2006 A/G UNPHASED TDT P-value=0.835; WHAP TDT P-value=0.393 UNPHASED TDT P-value=0.835; WHAP TDT P-value=0.393 no significant association was observed no significant association was observed Non-significant

SNP related genes (count: 2)

Literature-origin genes (count: 1)

Genes from other sources Help (count: 1)


SNPs in LD with rs1889189 (count: 12) View in gBrowse (chr20:10169643..10197086 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 12)