ADHDgene Database

SNP Report

Basic Info

Name	rs1800464 dbSNP Ensembl
Location	ChrX:43571197(Fwd)
Variant Alleles	A/C
Ancestral Allele	C
Functional Annotation	5_prime_UTR_variant; nc_transcript_variant; non_coding_exon_variant; synonymous_variant.
Consequence to Transcript	5_prime_UTR_variant(ENST00000542639) nc_transcript_variant(ENST00000497485) non_coding_exon_variant(ENST00000497485) synonymous_variant(ENST00000338702)
No. of Studies	2 (significant: 0; non-significant: 2; trend: 0)
Source	Literature-origin

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Hawi, Z., 2012	A:C	A	P-value=0.8185, X²=0.053, OR=1.11, 95% CI=0.46-2....... P-value=0.8185, X²=0.053, OR=1.11, 95% CI=0.46-2.66 More...	The marker did not show significant association with ADHD. The marker did not show significant association with ADHD.	Non-significant
Nyman ES, 2007			No available information. No available information.	No evidence of association was seen. No evidence of association was seen.	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
MAOA	monoamine oxidase A	Xp11.4-p11.3	20(13/7/0)

SNPs in LD with rs1800464 (count: 8) View in gBrowse (chrX:43551400..43609617 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs3027405	intron_variant	1.0[CEU]; 1.0[GIH]
rs3027406	intron_variant; upstream_gene_variant	1.0[CEU]; 1.0[GIH]
rs3027392	intron_variant; nc_transcript_variant	1.0[CEU]
rs7052785	downstream_gene_variant	1.0[CEU]; 1.0[GIH]
rs28375424	intron_variant; nc_transcript_variant	0.844[ASW]; 1.0[MEX]; 0.823[MKK]; 0.826[YRI]
rs3027409	downstream_gene_variant	1.0[CEU]; 1.0[GIH]
rs9330645	intron_variant; nc_transcript_variant	0.844[ASW]; 1.0[MEX]; 0.822[MKK]; 0.824[YRI]
rs3027404	intron_variant	1.0[CEU]