ADHDgene Database

SNP Report

Basic Info

Name	rs1800464 dbSNP Ensembl
Location	chrX:43571197(Fwd)
Variant Alleles	A/C
Ancestral Allele	C
Functional Annotation	5_prime_UTR_variant; nc_transcript_variant; non_coding_exon_variant; synonymous_variant.
Consequence to Transcript	5_prime_UTR_variant(ENST00000542639) nc_transcript_variant(ENST00000497485) non_coding_exon_variant(ENST00000497485) synonymous_variant(ENST00000338702)
No. of Studies	2 (significant: 0; non-significant: 2; trend: 0)
Source	Literature-origin

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Nyman ES, 2007			No available information. No available information.	No evidence of association was seen. No evidence of association was seen.	Non-significant
Hawi, Z., 2012	A:C	A	P-value=0.8185, X²=0.053, OR=1.11, 95% CI=0.46-2....... P-value=0.8185, X²=0.053, OR=1.11, 95% CI=0.46-2.66 More...	The marker did not show significant association with ADHD. The marker did not show significant association with ADHD.	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
MAOA	monoamine oxidase A	Xp11.4-p11.3	20(13/7/0)

SNPs in LD with rs1800464 (count: 8) View in gBrowse (chrX:43551400..43609617 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs3027406	intron_variant; upstream_gene_variant	1.0[CEU]; 1.0[GIH]
rs3027392	intron_variant; nc_transcript_variant	1.0[CEU]
rs9330645	intron_variant; nc_transcript_variant	0.844[ASW]; 1.0[MEX]; 0.822[MKK]; 0.824[YRI]
rs3027409	downstream_gene_variant	1.0[CEU]; 1.0[GIH]
rs28375424	intron_variant; nc_transcript_variant	0.844[ASW]; 1.0[MEX]; 0.823[MKK]; 0.826[YRI]
rs7052785	downstream_gene_variant	1.0[CEU]; 1.0[GIH]
rs3027405	intron_variant	1.0[CEU]; 1.0[GIH]
rs3027404	intron_variant	1.0[CEU]