ADHDgene Database

SNP Report

Basic Info

Name	rs17057305 dbSNP Ensembl
Location	Chr5:159381080(Fwd)
Variant Alleles	G/A
Ancestral Allele	G
Functional Annotation	intron_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000306675) upstream_gene_variant(ENST00000505218)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Hawi, Z., 2012	G:A	G	P-value=0.9319, X²=0.01, OR=1.01, 95% CI=0.72-1.4...... P-value=0.9319, X²=0.01, OR=1.01, 95% CI=0.72-1.41 More...	The marker did not show significant association with ADHD. The marker did not show significant association with ADHD.	Non-significant

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
ADRA1B	adrenergic, alpha-1B-, receptor	5q33.3	2(1/1/0)

Approved Symbol	Approved Name	Location
GAPDHP40	glyceraldehyde 3 phosphate dehydrogenase pseudogene 40	5q33.3

SNPs in LD with rs17057305 (count: 3) View in gBrowse (chr5:159344461..159381526 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs3896275	intron_variant; upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 1.0[MEX]; 1.0[TSI]
rs10515807	intron_variant	0.947[CHD]; 0.961[GIH]; 0.88[TSI]
rs3729604	synonymous_variant	0.811[CEU]; 0.832[CHD]