ADHDgene Database

SNP Report

Basic Info

Name	rs1470750 dbSNP Ensembl
Location	Chr7:50576648(Fwd)
Variant Alleles	C/G
Ancestral Allele	C
Functional Annotation	NMD_transcript_variant; intron_variant.
Consequence to Transcript	NMD_transcript_variant(ENST00000444733) intron_variant(ENST00000444124; ENST00000357936; ENST00000431062; ENST00000444733; ENST00000426377; ENST00000380984; ENST00000430300)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Guan L, 2009			single SNP association analyses: Nominal P-value=0.047, Empi...... single SNP association analyses: Nominal P-value=0.047, Empirical P-value=0.361 for ADHD-I More...	non-significant for ADHD, but achieve nominal significance f...... non-significant for ADHD, but achieve nominal significance for ADHD-I More...	Significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
DDC	dopa decarboxylase (aromatic L-amino acid decarboxylase)	7p11	6(5/1/0)

SNPs in LD with rs1470750 (count: 7) View in gBrowse (chr7:50546925..50664922 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.


rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]
rs1451371	NMD_transcript_variant; intron_variant	1(1/0/0)	0.806[CEU]

rs_ID	Functional Annotation	r²[population]
rs10899736	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.83[CEU]
rs3823674	NMD_transcript_variant; intron_variant	0.83[CEU]
rs12540874	intron_variant; nc_transcript_variant; upstream_gene_variant	0.815[CEU]
rs12718574	NMD_transcript_variant; intron_variant	0.801[CEU]
rs12718572	NMD_transcript_variant; intron_variant	1.0[CEU]; 0.939[CHB]; 0.933[JPT]
rs3807566	NMD_transcript_variant; intron_variant	0.835[CEU]