ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs1451371 dbSNP Ensembl
Location	chr7:50553051(Fwd)
Variant Alleles	T/C
Ancestral Allele	T
Functional Annotation	intron_variant; NMD_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000357936; ENST00000426377; ENST00000430300; ENST00000431062; ENST00000444124; ENST00000444733) NMD_transcript_variant(ENST00000444733)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Guan L, 2009			single SNP association analyses: Nominal P-value=0.036, Empi...... single SNP association analyses: Nominal P-value=0.036, Empirical P-value=0.276 for ADHD; Nominal P-value=0.012, Empirical P-value=0.116 for ADHD-I More...	achieve nominal significance for ADHD and ADHD-I achieve nominal significance for ADHD and ADHD-I	Significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
DDC	dopa decarboxylase (aromatic L-amino acid decarboxylase)	7p12.1	6(5/1/0)

Genes from other sources (count: 0)

SNPs in LD with rs1451371 (count: 32) View in gBrowse (chr7:50533539..50573848 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 32)

rs_ID	Functional Annotation	r²[population]
rs4329234	intron_variant; nc_transcript_variant; NMD_transcript_variant	0.823[CHB]
rs7785224	intron_variant; NMD_transcript_variant	0.9[JPT]
rs11575457	intron_variant; nc_transcript_variant; NMD_transcript_variant; non_coding_exon_variant	1.0[CHB]; 0.952[JPT]
rs4947582	intron_variant; NMD_transcript_variant	0.877[CEU]; 1.0[CHB]; 1.0[JPT]
rs11768267	intron_variant; nc_transcript_variant; NMD_transcript_variant	0.86[CHB]; 0.805[JPT]
rs4992502	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CHB]; 0.952[JPT]
rs10899734	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CHB]; 0.952[JPT]
rs12718541	intron_variant; NMD_transcript_variant; upstream_gene_variant	1.0[CHB]; 0.948[JPT]
rs7803247	intron_variant; nc_transcript_variant; NMD_transcript_variant	0.817[CHB]
rs4580999	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CHB]; 0.952[JPT]
rs12718574	intron_variant; NMD_transcript_variant	1.0[CEU]; 0.828[CHB]; 0.846[YRI]
rs2876827	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CHB]; 0.887[JPT]
rs12718529	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CHB]; 0.949[JPT]
rs11980368	intron_variant; NMD_transcript_variant; upstream_gene_variant	1.0[CHB]; 0.952[JPT]
rs730092	intron_variant; nc_transcript_variant; NMD_transcript_variant	0.824[CHB]; 0.808[JPT]
rs3807566	intron_variant; NMD_transcript_variant	1.0[CEU]; 0.813[CHB]
rs10899736	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs2122822	intron_variant; NMD_transcript_variant; upstream_gene_variant	1.0[CHB]; 0.951[JPT]
rs3887825	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CHB]; 0.952[JPT]
rs4579483	intron_variant; nc_transcript_variant; NMD_transcript_variant	0.954[CHB]; 0.951[JPT]
rs13311361	intron_variant; NMD_transcript_variant; upstream_gene_variant	1.0[CHB]; 0.952[JPT]
rs4433100	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CHB]; 0.903[JPT]
rs12718527	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CHB]; 0.952[JPT]
rs4947577	intron_variant; NMD_transcript_variant; upstream_gene_variant	1.0[CHB]; 0.952[JPT]
rs12718572	intron_variant; NMD_transcript_variant	0.833[CEU]
rs2329365	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CHB]; 0.951[JPT]
rs1451372	intron_variant; NMD_transcript_variant	1.0[CHB]; 0.952[JPT]
rs3823674	intron_variant; NMD_transcript_variant	1.0[CEU]; 0.823[CHB]
rs4948196	intron_variant; NMD_transcript_variant; upstream_gene_variant	1.0[CHB]; 0.952[JPT]
rs11238138	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CHB]; 0.952[JPT]
rs10899735	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CHB]; 0.952[JPT]
rs12718528	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CHB]; 0.952[JPT]