ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs12690808 dbSNP Ensembl
Location	Chr7:34606336(Fwd)
Variant Alleles	G/T
Ancestral Allele	T
Functional Annotation	downstream_gene_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000358772) intron_variant(ENST00000419766; ENST00000539747; ENST00000537560) nc_transcript_variant(ENST00000419766; ENST00000439852; ENST00000539747; ENST00000537560) non_coding_exon_variant(ENST00000439852)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Neale BM, 2010 (b)	T:G		GLM P-value=3.72E-05, meta-analysis P-value=0.3395 GLM P-value=3.72E-05, meta-analysis P-value=0.3395	One of the top 100 SNPs from imputed IMAGE II dataset One of the top 100 SNPs from imputed IMAGE II dataset	Non-significant

SNP related genes (count: 1)

Literature-origin genes (count: 0)

Genes from other sources (count: 1)

Approved Symbol	Approved Name	Location
NPSR1-AS1	NPSR1 antisense RNA 1	7p14.3

SNPs in LD with rs12690808 (count: 69) View in gBrowse (chr7:21106269..34696545 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 4)

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs2893482	intron_variant; nc_transcript_variant	1(0/1/0)	0.82[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.854[LWK]; 0.903[MEX]; 0.941[MKK]; 1.0[TSI]; 0.919[YRI]
rs1023556	intron_variant; nc_transcript_variant; upstream_gene_variant	1(0/1/0)	0.831[CEU]; 0.931[GIH]; 0.81[MEX]; 0.846[TSI]
rs6462569	intron_variant; nc_transcript_variant	1(0/1/0)	0.831[ASW]; 1.0[CEU]; 0.908[CHB]; 0.952[CHD]; 1.0[GIH]; 1.0[JPT]; 0.86[LWK]; 0.952[MEX]; 0.943[MKK]; 1.0[TSI]; 0.922[YRI]
rs10258145	intron_variant; nc_transcript_variant	1(0/1/0)	0.883[ASW]; 1.0[CEU]; 0.869[CHB]; 0.953[CHD]; 1.0[GIH]; 0.805[JPT]; 0.975[LWK]; 1.0[MEX]; 0.961[MKK]; 1.0[TSI]; 0.919[YRI]

LD-proxies (count: 65)

rs_ID	Functional Annotation	r²[population]
rs10951419	intron_variant; nc_transcript_variant	0.943[CEU]; 1.0[CHB]; 1.0[JPT]; 0.901[YRI]
rs4141269	intron_variant; nc_transcript_variant	0.883[CEU]; 0.818[CHB]
rs10245143	intron_variant; nc_transcript_variant	0.907[TSI]
rs975214	intron_variant; nc_transcript_variant	0.863[CHB]
rs6955901	intron_variant; nc_transcript_variant	0.825[CEU]; 0.818[CHB]
rs10261506	intron_variant; nc_transcript_variant	0.825[CEU]; 0.818[CHB]
rs4313062	intron_variant; nc_transcript_variant	0.807[CHB]
rs10229982	intron_variant; nc_transcript_variant	0.818[CHB]; 0.833[CHD]; 0.82[GIH]; 0.81[MEX]
rs12672538	intron_variant; nc_transcript_variant	0.827[CEU]; 0.908[CHB]; 0.927[CHD]; 0.804[GIH]; 0.949[JPT]
rs2108735	downstream_gene_variant; intron_variant; nc_transcript_variant	0.956[YRI]
rs740514	intron_variant; nc_transcript_variant	0.827[CEU]; 0.911[CHB]; 0.885[CHD]; 0.845[GIH]; 1.0[JPT]; 0.858[MEX]
rs6962591	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 0.919[YRI]
rs991101	intron_variant; nc_transcript_variant	0.818[CHB]
rs1894767	downstream_gene_variant; intron_variant; nc_transcript_variant	0.818[CHB]
rs10486649	intron_variant; nc_transcript_variant	0.827[CEU]; 1.0[CHB]; 1.0[CHD]; 0.845[GIH]; 1.0[JPT]; 0.81[MEX]
rs6462568	intron_variant; nc_transcript_variant	0.881[YRI]
rs10231845	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 0.919[YRI]
rs2079509	downstream_gene_variant; intron_variant; nc_transcript_variant	0.818[CHB]; 0.835[CHD]; 0.82[GIH]; 0.81[MEX]
rs10951421	intron_variant; nc_transcript_variant	0.814[CHB]
rs10951422	intron_variant; nc_transcript_variant	0.808[CEU]; 0.802[CHB]
rs17169893	intron_variant; nc_transcript_variant	0.818[CHB]; 0.82[GIH]
rs10245758	intron_variant; nc_transcript_variant	0.8[GIH]
rs2392273	intron_variant; nc_transcript_variant	1.0[CHB]; 0.976[CHD]; 0.845[GIH]; 1.0[JPT]; 0.81[MEX]
rs11982356	intron_variant; nc_transcript_variant	0.818[CHB]; 0.835[CHD]; 0.804[GIH]
rs17169871	intron_variant; nc_transcript_variant	0.849[TSI]; 0.819[YRI]
rs2190897	intron_variant; nc_transcript_variant	0.882[CEU]
rs1981606	intron_variant; nc_transcript_variant	0.878[CEU]; 0.908[CHB]; 1.0[JPT]
rs7810751	downstream_gene_variant; intron_variant; nc_transcript_variant	0.818[CHB]
rs17169876	intron_variant; nc_transcript_variant	0.813[YRI]
rs10277729	feature_elongation; intron_variant; nc_transcript_variant	0.871[CEU]; 0.836[JPT]
rs2609238	downstream_gene_variant; intron_variant; nc_transcript_variant	0.883[CEU]; 0.906[GIH]
rs10245221	intron_variant; nc_transcript_variant	0.907[TSI]
rs740515	intron_variant; nc_transcript_variant	0.827[CEU]; 1.0[CHB]; 1.0[CHD]; 0.845[GIH]; 1.0[JPT]; 0.857[MEX]
rs6947966	intron_variant; nc_transcript_variant	0.863[CHB]
rs10243426	downstream_gene_variant; intron_variant; nc_transcript_variant	0.818[CHB]; 0.833[CHD]; 0.82[GIH]; 0.8[MEX]
rs6955780	intron_variant; nc_transcript_variant	0.816[CEU]; 0.944[JPT]
rs7778336	intron_variant; nc_transcript_variant	0.802[CEU]; 1.0[CHB]; 1.0[JPT]
rs7810848	downstream_gene_variant; intron_variant; nc_transcript_variant	0.818[CHB]
rs990878	intron_variant; nc_transcript_variant	0.818[CHB]; 0.835[CHD]; 0.804[GIH]
rs10241719	intron_variant; nc_transcript_variant	0.818[CHB]; 0.8[GIH]
rs2392274	intron_variant; nc_transcript_variant	0.818[CHB]; 0.835[CHD]; 0.82[GIH]; 0.81[MEX]
rs12701367	intron_variant; nc_transcript_variant	0.878[CEU]; 0.906[CHB]; 1.0[JPT]
rs763895	intron_variant; nc_transcript_variant	0.818[CHB]
rs10239558	downstream_gene_variant; intron_variant; nc_transcript_variant	0.96[YRI]
rs13229729	intron_variant; nc_transcript_variant	0.878[CEU]; 1.0[CHB]; 1.0[JPT]
rs7794648	intron_variant; nc_transcript_variant	0.818[CHB]
rs10234226	downstream_gene_variant; intron_variant; nc_transcript_variant	0.818[CHB]
rs11976127	intron_variant; nc_transcript_variant	0.819[CEU]; 1.0[CHB]; 1.0[JPT]; 0.813[YRI]
rs12667480	intron_variant; nc_transcript_variant	0.818[CHB]
rs1023555	intron_variant; nc_transcript_variant; upstream_gene_variant	0.831[CEU]
rs7781421	intron_variant; nc_transcript_variant	0.878[TSI]; 0.922[YRI]
rs6963063	intron_variant; nc_transcript_variant	0.809[CHB]
rs1362165	downstream_gene_variant; intron_variant; nc_transcript_variant	0.818[CHB]
rs10280933	intron_variant; nc_transcript_variant	0.818[CHB]
rs1419774	downstream_gene_variant; intron_variant; nc_transcript_variant	0.813[CHB]; 0.833[CHD]; 0.819[GIH]; 0.81[MEX]
rs11976817	intron_variant; nc_transcript_variant	0.827[CEU]; 0.911[CHB]; 0.822[YRI]
rs13438112	downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 0.959[YRI]
rs10273188	intron_variant; nc_transcript_variant	0.818[CHB]
rs17169889	intron_variant; nc_transcript_variant	0.878[CEU]; 0.908[CHB]; 0.949[JPT]
rs6954620	intron_variant; nc_transcript_variant	0.818[CHB]
rs10272610	intron_variant; nc_transcript_variant	0.941[CEU]; 1.0[CHB]; 1.0[JPT]; 0.876[YRI]
rs1362202	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 0.881[YRI]
rs10238050	intron_variant; nc_transcript_variant	0.802[CHB]
rs7790795	intron_variant; nc_transcript_variant	0.818[CHB]
rs2097960	downstream_gene_variant; intron_variant; nc_transcript_variant	0.818[CHB]; 0.835[CHD]; 0.82[GIH]; 0.81[MEX]