ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs1023556 dbSNP Ensembl
Location	Chr7:34696545(Fwd)
Variant Alleles	C/T
Ancestral Allele	T
Functional Annotation	intron_variant; nc_transcript_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000439852; ENST00000419766; ENST00000358772; ENST00000539747; ENST00000431669; ENST00000537560; ENST00000535640; ENST00000399077; ENST00000544556) nc_transcript_variant(ENST00000439852; ENST00000419766; ENST00000358772; ENST00000539747; ENST00000431669; ENST00000537560; ENST00000535640; ENST00000544556) upstream_gene_variant(ENST00000381542; ENST00000465305; ENST00000381553; ENST00000381544; ENST00000360581; ENST00000396095; ENST00000531252; ENST00000359791; ENST00000381539)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Neale BM, 2010 (b)	T:C		GLM P-value=2.61E-05, meta-analysis P-value=0.4215 GLM P-value=2.61E-05, meta-analysis P-value=0.4215	One of the top 100 SNPs from imputed IMAGE II dataset One of the top 100 SNPs from imputed IMAGE II dataset	Non-significant

SNP related genes (count: 2)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
NPSR1	neuropeptide S receptor 1	7p14.3	1(0/1/0)

Genes from other sources (count: 1)

Approved Symbol	Approved Name	Location
NPSR1-AS1	NPSR1 antisense RNA 1	7p14.3

SNPs in LD with rs1023556 (count: 52) View in gBrowse (chr7:21106269..34696545 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 4)

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs12690808	downstream_gene_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant	1(0/1/0)	0.831[CEU]; 0.931[GIH]; 0.81[MEX]; 0.846[TSI]
rs2893482	intron_variant; nc_transcript_variant	1(0/1/0)	0.831[CEU]; 0.931[GIH]; 0.849[TSI]
rs10258145	intron_variant; nc_transcript_variant	1(0/1/0)	0.83[CEU]; 0.931[GIH]; 0.81[MEX]; 0.849[TSI]
rs6462569	intron_variant; nc_transcript_variant	1(0/1/0)	0.831[CEU]; 0.931[GIH]; 0.856[MEX]; 0.849[TSI]

LD-proxies (count: 48)

rs_ID	Functional Annotation	r²[population]
rs4313062	intron_variant; nc_transcript_variant	0.859[CHB]; 0.944[JPT]
rs2097960	downstream_gene_variant; intron_variant; nc_transcript_variant	0.868[CHB]; 0.903[JPT]
rs10273188	intron_variant; nc_transcript_variant	0.868[CHB]; 0.903[JPT]
rs2079509	downstream_gene_variant; intron_variant; nc_transcript_variant	0.868[CHB]; 0.903[JPT]
rs10241719	intron_variant; nc_transcript_variant	0.868[CHB]; 0.817[CHD]; 0.903[JPT]
rs1023555	intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 0.951[JPT]; 1.0[YRI]
rs12667480	intron_variant; nc_transcript_variant	0.868[CHB]; 0.903[JPT]
rs6955901	intron_variant; nc_transcript_variant	0.887[CEU]; 0.868[CHB]; 0.903[JPT]
rs11982356	intron_variant; nc_transcript_variant	0.868[CHB]; 0.903[JPT]
rs10277729	feature_elongation; intron_variant; nc_transcript_variant	0.937[CEU]; 0.894[JPT]
rs975214	intron_variant; nc_transcript_variant	0.819[CHB]; 0.903[JPT]
rs6967315	downstream_gene_variant; intron_variant; nc_transcript_variant	0.815[CHB]; 0.899[JPT]
rs10243426	downstream_gene_variant; intron_variant; nc_transcript_variant	0.826[CEU]; 0.868[CHB]; 0.9[JPT]
rs10951422	intron_variant; nc_transcript_variant	0.808[CEU]; 0.95[CHB]; 0.901[JPT]
rs1894767	downstream_gene_variant; intron_variant; nc_transcript_variant	0.868[CHB]; 0.857[JPT]
rs4141269	intron_variant; nc_transcript_variant	0.943[CEU]; 0.868[CHB]; 0.903[JPT]
rs10245221	intron_variant; nc_transcript_variant	0.817[LWK]; 0.816[TSI]
rs7790795	intron_variant; nc_transcript_variant	0.868[CHB]; 0.903[JPT]
rs6955780	intron_variant; nc_transcript_variant	0.881[CEU]; 0.853[CHB]; 0.892[JPT]
rs10231845	intron_variant; nc_transcript_variant	0.831[CEU]
rs6962591	intron_variant; nc_transcript_variant	0.831[CEU]
rs7794270	downstream_gene_variant; intron_variant; nc_transcript_variant	0.85[CHB]; 0.894[JPT]
rs10951421	intron_variant; nc_transcript_variant	0.826[CEU]; 0.865[CHB]; 0.947[JPT]
rs1362165	downstream_gene_variant; intron_variant; nc_transcript_variant	0.868[CHB]; 1.0[JPT]
rs10261506	intron_variant; nc_transcript_variant	0.887[CEU]; 0.868[CHB]; 0.903[JPT]
rs2609238	downstream_gene_variant; intron_variant; nc_transcript_variant	0.943[CEU]; 0.881[GIH]
rs991101	intron_variant; nc_transcript_variant	0.868[CHB]; 0.903[JPT]
rs7810751	downstream_gene_variant; intron_variant; nc_transcript_variant	0.868[CHB]; 0.857[JPT]
rs7810848	downstream_gene_variant; intron_variant; nc_transcript_variant	0.868[CHB]; 0.857[JPT]
rs7794648	intron_variant; nc_transcript_variant	0.868[CHB]; 0.903[JPT]
rs10245143	intron_variant; nc_transcript_variant	0.816[TSI]
rs2392274	intron_variant; nc_transcript_variant	0.868[CHB]; 0.903[JPT]
rs990878	intron_variant; nc_transcript_variant	0.868[CHB]; 0.903[JPT]
rs10229982	intron_variant; nc_transcript_variant	0.868[CHB]; 0.903[JPT]
rs17169893	intron_variant; nc_transcript_variant	0.868[CHB]; 0.903[JPT]
rs6947966	intron_variant; nc_transcript_variant	0.826[CEU]; 0.819[CHB]; 0.903[JPT]
rs1419774	downstream_gene_variant; intron_variant; nc_transcript_variant	0.864[CHB]; 0.852[JPT]
rs763895	intron_variant; nc_transcript_variant	0.868[CHB]; 0.9[JPT]
rs2190897	intron_variant; nc_transcript_variant	0.942[CEU]
rs6954620	intron_variant; nc_transcript_variant	0.868[CHB]; 0.903[JPT]
rs13438112	downstream_gene_variant; intron_variant; nc_transcript_variant	0.831[CEU]
rs2530543	intron_variant; nc_transcript_variant; upstream_gene_variant	0.856[YRI]
rs6963063	intron_variant; nc_transcript_variant	0.861[CHB]; 0.897[JPT]
rs1894768	downstream_gene_variant; intron_variant; nc_transcript_variant	0.853[JPT]
rs10280933	intron_variant; nc_transcript_variant	0.868[CHB]; 0.903[JPT]
rs10234226	downstream_gene_variant; intron_variant; nc_transcript_variant	0.868[CHB]; 0.857[JPT]
rs10238050	intron_variant; nc_transcript_variant	0.856[CHB]; 0.903[JPT]
rs1362202	intron_variant; nc_transcript_variant	0.831[CEU]