ADHDgene Database

SNP Report

Basic Info

Name	rs12591646 dbSNP Ensembl
Location	Chr15:55919139(Fwd)
Variant Alleles	T/G
Ancestral Allele	T
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000389286)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Wigg KG, 2008	A/C		TDT P-value=0.025, X²=5.026 TDT P-value=0.025, X²=5.026	was significantly associated to ADHD was significantly associated to ADHD	Significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
PRTG	protogenin	15q21.3	1(1/0/0)

SNPs in LD with rs12591646 (count: 10) View in gBrowse (chr15:55884615..55930577 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs558290	intron_variant	1(0/1/0)	0.904[CHB]; 0.859[CHD]; 0.865[JPT]
rs7165971	intron_variant; splice_region_variant	1(1/0/0)	0.849[MKK]