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KEGG Pathway Report
Basic Info
| ID | hsa04978 |
|---|---|
| Name | Mineral absorption |
| Description | Minerals are one of the five fundamental groups of nutrients needed to sustain life. Of the minerals, calcium plays innumerable roles in our bodies, serving as a main component of bone as well as an intracellular messenger in muscle contraction/relaxation, neural networks, the immune system, and endocrine/exocrine cells. Iron, copper, and other metals are required for redox reactions (as cofactors) and for oxygen transport and binding (in hemoglobin and myoglobin). Many enzymes require specific metal atoms to complete their catalytic functions. Animal tissues need moderate quantities of some elements (Ca, P, K, Na, Mg, S, and Cl) and trace amounts of others (Mn, Fe, I, Co, Cr, Cu, Zn, and Se). The minerals are absorbed by either passive or active transport systems through the intestinal mucosa, often using specialized transport proteins, such as ferritin for Fe3+ and vitamin D-induced protein for calcium. |
| No. of Genes in ADHDgene | 7 |
| Source | Pathway by Database Search |
Pathway related genes in ADHDgene (count: 7)
Literature-origin genes (count: 0)
Genes from other sources 
(count: 7)
| Approved Symbol | Approved Name | Location | Source |
|---|---|---|---|
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 | 2q35 | Mapped by significant region |
| SLC31A1 | solute carrier family 31 (copper transporters), member 1 | 9q31-q32 | Mapped by significant region |
| FXYD2 | FXYD domain containing ion transport regulator 2 | 11q23 | Mapped by significant region |
| STEAP2 | six transmembrane epithelial antigen of the prostate 2 | 7q21.13 | Mapped by PBA pathway |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 | 7q34 | Mapped by PBA pathway |
| FTH1 | ferritin, heavy polypeptide 1 | 11q13 | Mapped by significant region |
| SLC34A2 | solute carrier family 34 (sodium phosphate), member 2 | 4p15.2 | Mapped by CNV |