ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Other Variant Report

Basic Info
Name DRD2_TaqI
Type point mutation
Related Gene DRD2
No. of Study 5 (significant: 1; non-significant 4; trend: 0)

Variant related studies (count: 5)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Rowe DC, 1999 A1/A2 A1 X2 test: P=0.035 (df=1) for additive genetic effe...... X2 test: P=0.035 (df=1) for additive genetic effects on HI symptoms in the situation without parental mating types as controls; P=0.003 (df=2) for additive plus dominance genetic effects on HI symptoms in the situation without parental mating types as controls. More... None of the results with the test that included parental mat...... None of the results with the test that included parental mating types as controls were significant. More... Non-significant
Comings DE, 1991 A1/A2 A1 chi-square P-value=0.0003, X2-1=14.64 for ADHD co...... chi-square P-value=0.0003, X2-1=14.64 for ADHD compared with the total controls; chi-square P-value=0.0001, X2-2=17.30 for ADHD compared with the controls known to be nonalcoholic; chi-square P-value=0.02, X2-1=5.26 for ADHD secondary to TS compared with the total controls; chi-square P-value=0.002, X2-2=10.00 for ADHD compared with the controls known to be nonalcoholic; chi-square P-value=0.0001, X2-1=17.44 for ADHD and ADHD secondary to TS compared with the total controls; chi-square P-value=0.0001, X2-2=18.66 for ADHD and ADHD secondary to TS compared with the controls known to be nonalcoholic More... The prevalence of the A1 allele was significantly increased ...... The prevalence of the A1 allele was significantly increased in patients with ADHD. More... Significant
Huang YS, 2003 A1/A2 allelic HHRR P-value=0.557, X2=0.3 in total; alle...... allelic HHRR P-value=0.557, X2=0.3 in total; allelic HHRR P-value=0.842, X2=0.04 in sporadic cases; allelic HHRR P-value=0.273, X2=1.2 in familial cases; allelic HHRR P-value=0.544, X2=0.4 in male; allelic HHRR P-value=0.952, X2=0.004 in female More... there was no significant difference in transmission rates be...... there was no significant difference in transmission rates between DRD2 TaqI A1 and A2 alleles More... Non-significant
Kirley A, 2002 HHRR: P-value=0.18 (RR=1.2, OR=1.5); TDT: P-value=0.511 (OR=...... HHRR: P-value=0.18 (RR=1.2, OR=1.5); TDT: P-value=0.511 (OR=1.31); TDT by presence of family history: P-value=0.238 (OR[95%CI]=0.32[0.06-1.64]); TDT of Paternal and Maternal transmissions: P-value=0.67 (OR[95%CI]=0.71[0.15-3.33]) More... trends for association trends for association Non-significant
Kustanovich V, 2004 GRR=1.43, TDT P-value=0.583 GRR=1.43, TDT P-value=0.583 No evidence for an association was found No evidence for an association was found Non-significant