ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

GO Report

Basic Info

ID	GO:0035999
Name	tetrahydrofolate interconversion
Type	Biological Process
No. of Genes in ADHDgene	4
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 4)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
MTHFR	methylenetetrahydrofolate reductase (NAD(P)H)	1p36.3	1(0/1/0)

Genes from other sources (count: 3)

Approved Symbol	Approved Name	Source	Evidence[PMID]
MTHFD2L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like	Mapped by CNV
SHMT1	serine hydroxymethyltransferase 1 (soluble)	Mapped by significant region
SHMT2	serine hydroxymethyltransferase 2 (mitochondrial)	Mapped by CNV