ADHDgene Database

Gene Report

Basic Info

Approved Symbol	NLN
Previous Symbol	AGTBP
Symbol Alias	KIAA1226
Approved Name	neurolysin (metallopeptidase M3 family)
Previous Name	"angiotensin binding protein"
Location	5q12.3
Position	chr5:65018023-65167553, 1
External Links	HGNC: 16058 Entrez Gene: 57486 Ensembl: ENSG00000123213 UCSC: uc003juf.3
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

Gene related studies (count: 1)

Reference	Statistical Values/Author Comments	Result of Statistical Analysis
Elia, J., 2012	This gene was found directly affected by CNVRs overrepresented in individuals with ADHD.	Significant

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 4)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006508	proteolysis	biological process	IEA	123
GO:0004222	metalloendopeptidase activity	molecular function	IEA	36
GO:0005758	mitochondrial intermembrane space	cellular component	IEA	12
GO:0046872	metal ion binding	molecular function	IEA	200

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04614	Renin-angiotensin system	4

Genes shared at least 5 GO terms with NLN (count: 0)

Genes shared at least 2 KEGG pathways with NLN (count: 0)

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Region: chr5:65018023..65167553 View in gBrowse