ADHDgene Database

SNP Report

Basic Info

Name	rs7854469 dbSNP Ensembl
Location	chr9:93372229(Fwd)
Variant Alleles	T/A
Ancestral Allele	T
Functional Annotation	3_prime_UTR_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000375765)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Reif, A., 2011	T/A		P-value=0.0394, OR (allele)=1.40 (T), 95% CI=1.02-1.93 in Ge...... P-value=0.0394, OR (allele)=1.40 (T), 95% CI=1.02-1.93 in German discovery sample; P-value=0.072, OR (allele)=1.19 (A), 95% CI=0.98-1.43 in IMpACT replication sample; P-value=0.6023, OR (allele)=1.04 (A), 95% CI=0.89-1.23 in pooled data; PDT P-value=0.2059 for allele T in the family-based analysis More...	4 out of 12 investigated SNPs had p<0.05 in the association ...... 4 out of 12 investigated SNPs had p<0.05 in the association test with aADHD. Replication in 1035 aADHD patients and 1381 controls from IMpACT did not show any significant SNP association. More...	Significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
DIRAS2	DIRAS family, GTP-binding RAS-like 2	9q22.32	1(1/0/0)

SNPs in LD with rs7854469 (count: 1) View in gBrowse (chr9:93366369..93372229 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.