ADHDgene Database

SNP Report

Basic Info

Name	rs755203 dbSNP Ensembl
Location	Chr20:61994264(Fwd)
Variant Alleles	G/A
Ancestral Allele	G
Functional Annotation	intron_variant; nc_transcript_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000463705; ENST00000370257) nc_transcript_variant(ENST00000463705; ENST00000370257) upstream_gene_variant(ENST00000467563; ENST00000498043; ENST00000370263)
No. of Studies	2 (significant: 1; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Guan L, 2009			single SNP association analyses: Nominal P-value=0.032, Empi...... single SNP association analyses: Nominal P-value=0.032, Empirical P-value=0.19 for ADHD-I More...	non-significant for ADHD, but achieve nominal significance f...... non-significant for ADHD, but achieve nominal significance for ADHD-I More...	Significant
Lee J, 2008	G/A		P-value=0.837, X² (1df)=0.042 in all subtypes; P-...... P-value=0.837, X² (1df)=0.042 in all subtypes; P-value=0.793, X² (1df)=0.069 in inattentive subtype; P-value=0.578, X² (1df)=0.31 in combined subtype More...	no significant evidence of association no significant evidence of association	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
CHRNA4	cholinergic receptor, nicotinic, alpha 4	20	7(4/3/0)

SNPs in LD with rs755203 (count: 1) View in gBrowse (chr20:61981134..61994264 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.