ADHDgene Database

SNP Report

Basic Info

Name	rs719452 dbSNP Ensembl
Location	Chr1:115837057(Fwd)
Variant Alleles	A/T
Ancestral Allele	T
Functional Annotation	intron_variant; nc_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000369512; ENST00000425449; LRG_260_t1) nc_transcript_variant(ENST00000425449)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Ribases M, 2008			genotypic P-value=0.1; genotypic P-value=0.033, OR=1.35 (1.0...... genotypic P-value=0.1; genotypic P-value=0.033, OR=1.35 (1.02-1.78) in dominant model; genotypic P-value=0.45 in recessive model; allelic P-value=0.046, OR=1.25 (1-1.56) in Children More...	provided evidence of association with childhood ADHD provided evidence of association with childhood ADHD	Significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
NGF	nerve growth factor (beta polypeptide)	1p13.1	2(2/0/0)

SNPs in LD with rs719452 (count: 16) View in gBrowse (chr1:115833581..115857958 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs910330	intron_variant; nc_transcript_variant	1(0/1/0)	0.812[JPT]
rs2254404	intron_variant; nc_transcript_variant	1(1/0/0)	0.817[CHB]; 0.944[JPT]

rs_ID	Functional Annotation	r²[population]
rs1318345	intron_variant; nc_transcript_variant	0.825[CHB]; 0.95[JPT]
rs4406631	intron_variant; nc_transcript_variant	0.856[CEU]
rs4567277	intron_variant; nc_transcript_variant	0.862[CHB]; 0.95[JPT]
rs7555016	intron_variant; nc_transcript_variant	0.952[CHB]; 1.0[JPT]
rs2747058	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 0.947[JPT]
rs6678788	intron_variant; nc_transcript_variant	0.812[JPT]
rs2254527	intron_variant; nc_transcript_variant	1.0[CEU]; 0.952[CHB]; 0.947[JPT]
rs6678898	intron_variant; nc_transcript_variant	1.0[CEU]; 0.945[CHB]; 1.0[JPT]; 1.0[YRI]
rs4146585	intron_variant; nc_transcript_variant	0.951[CHB]; 1.0[JPT]
rs4839434	intron_variant; nc_transcript_variant	0.94[CHB]; 1.0[JPT]; 1.0[YRI]
rs10776797	intron_variant; nc_transcript_variant	0.952[CHB]; 1.0[JPT]
rs2239622	intron_variant; nc_transcript_variant	0.823[CHB]; 0.948[JPT]
rs4382725	intron_variant; nc_transcript_variant	0.953[CHB]; 1.0[JPT]
rs4573519	intron_variant; nc_transcript_variant	0.905[CHB]; 1.0[JPT]