ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs6944090 dbSNP Ensembl
Location	chr7:50573140(Fwd)
Variant Alleles	T/C
Ancestral Allele	T
Functional Annotation	intron_variant; NMD_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000357936; ENST00000380984; ENST00000426377; ENST00000430300; ENST00000431062; ENST00000444124; ENST00000444733) NMD_transcript_variant(ENST00000444733)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Ribases M, 2009(b)			Case-control test: lowest P-value=0.025 for genotype analysi...... Case-control test: lowest P-value=0.025 for genotype analysis, P-value=0.077 for allele analysis in childhood combined ADHD. More...	no significance after correcting for multiple comparisons no significance after correcting for multiple comparisons	Significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
DDC	dopa decarboxylase (aromatic L-amino acid decarboxylase)	7p12.1	6(5/1/0)

Genes from other sources (count: 0)

SNPs in LD with rs6944090 (count: 33) View in gBrowse (chr7:50454736..50614076 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 33)

rs_ID	Functional Annotation	r²[population]
rs6592963	intron_variant; NMD_transcript_variant	0.901[CEU]
rs2122817	intron_variant; NMD_transcript_variant	0.888[CHB]
rs17634717	intron_variant; nc_transcript_variant; NMD_transcript_variant	0.904[CHB]
rs2876830	downstream_gene_variant; intron_variant; NMD_transcript_variant; upstream_gene_variant	0.877[CHB]
rs12535064	downstream_gene_variant; intron_variant; NMD_transcript_variant	0.901[CEU]
rs11575553	3_prime_UTR_variant; downstream_gene_variant; nc_transcript_variant; NMD_transcript_variant; non_coding_exon_variant	0.811[CHB]; 0.827[CHD]
rs6959427		0.81[CHB]
rs3807553	downstream_gene_variant; intron_variant; nc_transcript_variant; NMD_transcript_variant; non_coding_exon_variant; upstream_gene_variant	0.904[CHB]; 0.846[CHD]
rs11575321	intron_variant; nc_transcript_variant; NMD_transcript_variant	0.904[CHB]
rs11575548	intron_variant; nc_transcript_variant; NMD_transcript_variant; upstream_gene_variant	0.904[CHB]; 0.923[CHD]
rs17634958	intron_variant; NMD_transcript_variant; upstream_gene_variant	0.904[CHB]; 0.923[CHD]
rs3735274	intron_variant; nc_transcript_variant; NMD_transcript_variant; upstream_gene_variant	0.901[CEU]
rs17635123	intron_variant; NMD_transcript_variant	0.904[CHB]
rs2100280	intron_variant; NMD_transcript_variant	0.895[CEU]
rs11575282	downstream_gene_variant; intron_variant; NMD_transcript_variant; upstream_gene_variant	0.904[CHB]; 0.846[CHD]
rs11976368		0.811[CHB]; 0.85[CHD]
rs10499691		0.811[CHB]; 0.85[CHD]
rs9918702	downstream_gene_variant; intron_variant; NMD_transcript_variant	0.901[CEU]
rs1349491	downstream_gene_variant; intron_variant; NMD_transcript_variant; upstream_gene_variant	0.904[CHB]
rs10249982	downstream_gene_variant; intron_variant; NMD_transcript_variant	0.901[CEU]
rs2329367	intron_variant; NMD_transcript_variant; upstream_gene_variant	0.904[CHB]
rs11575338	intron_variant; nc_transcript_variant; NMD_transcript_variant; upstream_gene_variant	0.904[CHB]
rs7777600	downstream_gene_variant; intron_variant; NMD_transcript_variant	0.95[CEU]; 1.0[CHB]; 0.923[CHD]; 1.0[JPT]; 0.829[GIH]
rs11575313	intron_variant; nc_transcript_variant; NMD_transcript_variant	0.904[CHB]
rs11575286	downstream_gene_variant; intron_variant; NMD_transcript_variant; upstream_gene_variant	0.904[CHB]; 0.846[CHD]
rs2242041	intron_variant; nc_transcript_variant; NMD_transcript_variant; upstream_gene_variant	0.811[CHB]; 0.85[CHD]
rs1107743	intron_variant; NMD_transcript_variant	0.904[CHB]; 0.923[CHD]
rs11575322	intron_variant; nc_transcript_variant; NMD_transcript_variant	0.904[CHB]; 0.846[CHD]
rs7809234	downstream_gene_variant; intron_variant; nc_transcript_variant; NMD_transcript_variant; non_coding_exon_variant; upstream_gene_variant	1.0[JPT]
rs2167364	intron_variant; NMD_transcript_variant	0.834[CHB]; 0.808[CHD]
rs6962370	intron_variant; nc_transcript_variant	1.0[JPT]
rs12538830	downstream_gene_variant; intron_variant; NMD_transcript_variant	0.95[CEU]
rs7797772	intron_variant; nc_transcript_variant	0.811[CHB]; 0.85[CHD]