ADHDgene Database

SNP Report

Basic Info

Name	rs690111 dbSNP Ensembl
Location	Chr9:93377290(Fwd)
Variant Alleles	T/G
Ancestral Allele	T
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000375765)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Reif, A., 2011	G/T		P-value=0.3392, OR (allele)=1.11 (T), 95% CI=0.90-1.37 in Ge...... P-value=0.3392, OR (allele)=1.11 (T), 95% CI=0.90-1.37 in German discovery sample; P-value=0.8043, OR (allele)=1.02 (T), 95% CI=0.89-1.16 in IMpACT replication sample; P-value=0.4684, OR (allele)=1.04 (T), 95% CI=0.93-1.17 in pooled data; PDT P-value=0.4982 for allele G in the family-based analysis More...	This SNP did not reach p<0.05 in the association test with a...... This SNP did not reach p<0.05 in the association test with aADHD. Replication in 1035 aADHD patients and 1381 controls from IMpACT did not show any significant SNP association. More...	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
DIRAS2	DIRAS family, GTP-binding RAS-like 2	9q22.32	1(1/0/0)

SNPs in LD with rs690111 (count: 3) View in gBrowse (chr9:93369784..93380772 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs1017753	intron_variant	1(0/1/0)	0.964[YRI]
rs7868194	downstream_gene_variant	1(0/1/0)	0.86[YRI]