ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs6427957 dbSNP Ensembl
Location	chr1:202562427(Fwd)
Variant Alleles	G/A
Ancestral Allele	G
Functional Annotation	3_prime_UTR_variant; downstream_gene_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000367267; ENST00000367268) downstream_gene_variant(ENST00000336894; ENST00000367270; ENST00000391959; ENST00000608999)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Sanchez-Mora, C., 2012			P-value=0.016, Genotype12+22 vs11: P-value=0.004, OR(95%CI)=...... P-value=0.016, Genotype12+22 vs11: P-value=0.004, OR(95%CI)=1.47(1.13¨C1.92); Genotypes22 vs11+12: P-value=0.309, OR(95%CI)=1.15(0.88¨C1.52); allelic P-value=0,017, OR(95%CI)=1.22(1.04¨C1.43) More...	Nine SNPs located in five genes displayed nominal associatio...... Nine SNPs located in five genes displayed nominal associations in the comparison of ADHD children and controls More...	Significant

SNP related genes (count: 2)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
SYT2	synaptotagmin II	1q32.1	1(1/0/0)

Genes from other sources (count: 1)

Approved Symbol	Approved Name	Location
PPP1R12B	protein phosphatase 1, regulatory subunit 12B	1q32.1

SNPs in LD with rs6427957 (count: 27) View in gBrowse (chr1:202365332..202569877 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 27)

rs_ID	Functional Annotation	r²[population]
rs10158100	intron_variant; NMD_transcript_variant; upstream_gene_variant	0.857[CHB]
rs1467120	intron_variant; upstream_gene_variant	0.849[CHB]
rs12023106	intron_variant; NMD_transcript_variant	0.889[CHB]
rs3767404	intron_variant; nc_transcript_variant	0.857[CHB]
rs2362941	3_prime_UTR_variant; downstream_gene_variant	0.804[CHB]; 0.825[MEX]
rs3767425	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.857[CHB]
rs10159280	intron_variant; NMD_transcript_variant; upstream_gene_variant	0.85[CHB]
rs747640	3_prime_UTR_variant; downstream_gene_variant	0.857[CHB]; 0.825[MEX]
rs1832719	intron_variant; nc_transcript_variant	0.857[CHB]
rs2362282	downstream_gene_variant; intron_variant; nc_transcript_variant	0.857[CHB]
rs10800836	downstream_gene_variant; intron_variant; upstream_gene_variant	0.857[CHB]
rs2249811	intron_variant; nc_transcript_variant; upstream_gene_variant	0.857[CHB]
rs6666325	intron_variant	0.867[MEX]
rs6679552	intron_variant; nc_transcript_variant	0.851[CHB]
rs10800840	intron_variant; nc_transcript_variant	0.857[CHB]
rs925532	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.857[CHB]
rs6427958	3_prime_UTR_variant; downstream_gene_variant	0.85[CHB]
rs3767427	intron_variant; NMD_transcript_variant	0.855[CHB]
rs3767397	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.857[CHB]
rs10920410	intron_variant; nc_transcript_variant; upstream_gene_variant	0.807[CHB]
rs10494834	downstream_gene_variant; intron_variant	0.822[MEX]
rs3753908	intron_variant; nc_transcript_variant	0.857[CHB]
rs2292489	downstream_gene_variant; intron_variant; nc_transcript_variant	0.857[CHB]
rs1806606	intron_variant; nc_transcript_variant; upstream_gene_variant	0.857[CHB]
rs925533	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.857[CHB]
rs967677	intron_variant; nc_transcript_variant	0.857[CHB]; 0.825[MEX]
rs4950859	3_prime_UTR_variant; downstream_gene_variant	0.812[CHB]