ADHDgene Database

SNP Report

Basic Info

Name	rs6297 dbSNP Ensembl
Location	chr6:78171941(Fwd)
Variant Alleles	C/T
Ancestral Allele	T
Functional Annotation	downstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000369947)
No. of Studies	2 (significant: 1; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Ickowicz A, 2007	G/A	G	TDT P-value=0.816 TDT P-value=0.816	No evidence for biased transmission No evidence for biased transmission	Non-significant
Smoller JW, 2006	A/G		allelic P-value=0.039 in inattentive; allelic P-value=0.35 i...... allelic P-value=0.039 in inattentive; allelic P-value=0.35 in ADHD; allelic P-value=0.61 in combined More...	displayed nominally significant association with the inatten...... displayed nominally significant association with the inattentive subtype More...	Significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
HTR1B	5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled	6q13	14(5/9/0)

SNPs in LD with rs6297 (count: 17) View in gBrowse (chr6:78158883..78268916 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.