ADHDgene Database

SNP Report

Basic Info

Name	rs6077690 dbSNP Ensembl
Location	Chr20:10197461(Fwd)
Variant Alleles	A/T
Ancestral Allele	A
Functional Annotation	intron_variant; nc_transcript_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000421143; ENST00000453544; ENST00000426491; ENST00000451151) nc_transcript_variant(ENST00000421143; ENST00000453544; ENST00000426491; ENST00000451151) upstream_gene_variant(ENST00000304886; ENST00000254976; ENST00000430336)
No. of Studies	2 (significant: 1; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Kim JW, 2007	T/A	A	Combined TDT P-value=0.03 (OR=0.80); Single marker analysis ...... Combined TDT P-value=0.03 (OR=0.80); Single marker analysis FBAT P-value=0.375; Exploratory analyses FBAT P-value=0.301 for co-morbid CD, P-value=0.489 for co-morbid MDD, P-value=0.728 for co-morbid BD More...	Combined analysis showed evidence of significant association...... Combined analysis showed evidence of significant association with ADHD More...	Significant
Renner TJ, 2008			FAMHAP P-value=0.86 FAMHAP P-value=0.86	no significant preferential transmissions to affected childr...... no significant preferential transmissions to affected children with ADHD were detected More...	Non-significant

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
SNAP25	synaptosomal-associated protein, 25kDa	20p12-p11.2	18(13/5/0)

Approved Symbol	Approved Name	Location
SNAP25-AS1	SNAP25 antisense RNA 1	20p12.2

SNPs in LD with rs6077690 (count: 2) View in gBrowse (chr20:10194246..10197461 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs4813023	intron_variant; nc_transcript_variant	1(0/1/0)	0.825[CHB]; 0.953[JPT]