ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

SNP Report

Basic Info
Name rs550818 dbSNP Ensembl
Location chr17:27901975(Fwd)
Variant Alleles A/G
Ancestral Allele G
Functional Annotation downstream_gene_variant; intron_variant; missense_variant; nc_transcript_variant; NMD_transcript_variant.
Polyphen Annotation: benign(ENST00000579937)
Consequence to Transcript downstream_gene_variant(ENST00000301057; ENST00000378818; ENST00000491377; ENST00000577934; ENST00000578266; ENST00000578749; ENST00000579050; ENST00000579674; ENST00000580183; ENST00000581411; ENST00000581925; ENST00000582829; ENST00000583940; ENST00000585148; ENST00000586574)
intron_variant(ENST00000225394; ENST00000394869; ENST00000473217; ENST00000578670; ENST00000581348; ENST00000581474)
missense_variant(ENST00000579937)
nc_transcript_variant(ENST00000473217; ENST00000581474)
NMD_transcript_variant(ENST00000578670)
No. of Studies 2 (significant: 1; non-significant: 1; trend: 0)
Source Literature-origin

SNP related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Won H, 2011 C/T logistic regression P-value=0.0056, adjusted OR=2.66 for CT ...... logistic regression P-value=0.0056, adjusted OR=2.66 for CT genotype More... rs550818 (C>T), located in intron 20 of GIT1, associated wit...... rs550818 (C>T), located in intron 20 of GIT1, associated with ADHD susceptibility after Bonferroni correction (significance level alpha=0.050/8=0.00625) for multiple testing More... Significant
Salatino-Oliveira, A., 2012 C/T TT genotype: P-value=0.862, OR=1.087, 95% CI=0.42¨C2.79 for ...... TT genotype: P-value=0.862, OR=1.087, 95% CI=0.42¨C2.79 for model 1; P-value=0.245, OR=0.782, 95% CI=0.516¨C1.184 for model 2; CT genotype: P-value=0.184, OR=0.749, 95% CI=0.49¨C1.15 for model 1; CC genotype: OR=1 for model 1 and 2. TDT P-value=0.761, z =0.305 More... Adjusting for gender, age and IQ score, no effect of GIT1 ge...... Adjusting for gender, age and IQ score, no effect of GIT1 genotypes on ADHD susceptibility was observed in the case-control analysis. With the TDT test, we did not detect the overtransmission of any rs550818 allele (C or T ) from parents to ADHD children. More... Non-significant

SNP related genes (count: 3)

Literature-origin genes (count: 1)

Genes from other sources Help (count: 2)


SNPs in LD with rs550818 (count: 5) View in gBrowse (chr17:27895528..27907486 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 5)