ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

SNP Report

Basic Info
Name rs4633 dbSNP Ensembl
Location chr22:19950235(Fwd)
Variant Alleles C/T
Ancestral Allele C
Functional Annotation nc_transcript_variant; NMD_transcript_variant; non_coding_exon_variant; synonymous_variant; upstream_gene_variant.
Consequence to Transcript nc_transcript_variant(ENST00000467943)
NMD_transcript_variant(ENST00000207636)
non_coding_exon_variant(ENST00000467943)
synonymous_variant(ENST00000207636; ENST00000361682; ENST00000403184; ENST00000403710; ENST00000406520; ENST00000407537; ENST00000412786; ENST00000449653)
upstream_gene_variant(ENST00000428707; ENST00000493893; ENST00000585066)
No. of Studies 2 (significant: 1; non-significant: 1; trend: 0)
Source Literature-origin

SNP related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result of Statistical Analysis
Halleland H, 2009 C//T Single marker test: P-value=0.66 (OR=1.05 [0.86-1.27]) | Qua...... Single marker test: P-value=0.66 (OR=1.05 [0.86-1.27]) | Quantitative linear regression analysis: P-value=0.06 (beta=0.55) for hyperactivity subscale; P-value=0.30 (beta=-0.30) for inattention subscale; P-value=0.65 (beta=0.24) for ASRS total More... no association with ADHD, but tendenial association with hyp...... no association with ADHD, but tendenial association with hyperactivity/impulsivity. More... Non-significant
Michaelovsky E, 2008 C/T P-value=0.005, X2(1)=7.77 P-value=0.005, X2(1)=7.77 showed significant association with ADHD showed significant association with ADHD Significant

SNP related genes (count: 2)

Literature-origin genes (count: 1)

Genes from other sources Help (count: 1)


SNPs in LD with rs4633 (count: 3) View in gBrowse (chr22:19948863..19950763 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 3)