ADHDgene Database

SNP Report

Basic Info

Name	rs362584 dbSNP Ensembl
Location	Chr20:10254475(Fwd)
Variant Alleles	G/A
Ancestral Allele	G
Functional Annotation	intron_variant; nc_transcript_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000453544; ENST00000421143; ENST00000304886; ENST00000254976; ENST00000430336) nc_transcript_variant(ENST00000453544; ENST00000421143) upstream_gene_variant(ENST00000492814)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Kim JW, 2007	G/A	A	Single marker analysis FBAT P-value=0.456; Exploratory analy...... Single marker analysis FBAT P-value=0.456; Exploratory analyses FBAT P-value=0.763 for co-morbid CD, P-value=0.791 for co-morbid MDD, P-value=0.439 for co-morbid BD More...	No association was found between ADHD or co-morbidities of A...... No association was found between ADHD or co-morbidities of ADHD and this SNP More...	Non-significant

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
SNAP25	synaptosomal-associated protein, 25kDa	20p12-p11.2	18(13/5/0)

Approved Symbol	Approved Name	Location
SNAP25-AS1	SNAP25 antisense RNA 1	20p12.2

SNPs in LD with rs362584 (count: 2) View in gBrowse (chr20:10253082..10276221 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs362990	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.833[ASW]; 0.926[GIH]; 1.0[MEX]; 0.809[MKK]; 0.95[TSI]
rs362574	intron_variant; nc_transcript_variant; upstream_gene_variant	0.942[CHB]; 0.932[CHD]; 1.0[JPT]