ADHDgene Database

SNP Report

Basic Info

Name	rs362569 dbSNP Ensembl
Location	Chr20:10246733(Fwd)
Variant Alleles	T/C
Ancestral Allele	T
Functional Annotation	intron_variant; nc_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000453544; ENST00000304886; ENST00000254976; ENST00000421143; ENST00000430336) nc_transcript_variant(ENST00000453544; ENST00000421143)
No. of Studies	3 (significant: 0; non-significant: 3; trend: 0)
Source	Literature-origin

SNP related studies (count: 3)

Reference	Allele Change	Statistical Values	Author Comments	Result of Statistical Analysis
Feng Y, 2005(b)	T/C	allelic TDT P-value=0.68, X²=0.17 in Irvine sampl...... allelic TDT P-value=0.68, X²=0.17 in Irvine sample; allelic TDT P-value=0.142, X²=2.162 in Toronto sample More...	there was no significant result both in the Toronto sample a...... there was no significant result both in the Toronto sample and the Irvine sample More...	Non-significant
Sarkar, K., 2012	C/T	allelic P-value=0.58, X²=0.31 for case-control, P...... allelic P-value=0.58, X²=0.31 for case-control, P-value=0.46, X²=0.54 for family-based; genotypic P-value=0.05, X²=5.79 for case-control, P-value=0.51, X²=1.33 for family-based; X²=0.87, TDT P-value=0.35, Relative risk (95% CI)=1.5 (0.8¨C3.0) More...	Case-control analysis revealed lack of any significant diffe...... Case-control analysis revealed lack of any significant difference in allelic frequencies between ADHD probands, their parents and controls P>0.05. rs362569 and rs1051312 failed to reveal any preferential transmission. More...	Non-significant
Nyman ES, 2007		No available information. No available information.	No evidence of association was seen. No evidence of association was seen.	Non-significant

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
SNAP25	synaptosomal-associated protein, 25kDa	20p12-p11.2	18(13/5/0)

Approved Symbol	Approved Name	Location
SNAP25-AS1	SNAP25 antisense RNA 1	20p12.2

SNPs in LD with rs362569 (count: 6) View in gBrowse (chr20:10236231..10253082 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.


rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]
rs362562	intron_variant; nc_transcript_variant	1(0/1/0)	0.961[CEU]; 0.952[MEX]

rs_ID	Functional Annotation	r²[population]
rs6039795	intron_variant; nc_transcript_variant	0.848[CEU]; 0.928[CHB]; 0.877[JPT]
rs362574	intron_variant; nc_transcript_variant; upstream_gene_variant	0.848[CEU]; 0.866[TSI]
rs362547	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs363018	intron_variant; nc_transcript_variant	0.961[CEU]
rs362548	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 0.947[YRI]