ADHDgene Database

SNP Report

Basic Info

Name	rs2423486 dbSNP Ensembl
Location	Chr20:10212212(Fwd)
Variant Alleles	T/C
Ancestral Allele	T
Functional Annotation	intron_variant; nc_transcript_variant; non_coding_exon_variant.
Consequence to Transcript	intron_variant(ENST00000254976; ENST00000304886; ENST00000421143; ENST00000430336) nc_transcript_variant(ENST00000453544; ENST00000421143) non_coding_exon_variant(ENST00000453544)
No. of Studies	2 (significant: 0; non-significant: 2; trend: 0)
Source	Literature-origin

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Nyman ES, 2007			No available information. No available information.	No evidence of association was seen. No evidence of association was seen.	Non-significant
Kim JW, 2007	C/T	T	Single marker analysis FBAT P-value=0.481; Exploratory analy...... Single marker analysis FBAT P-value=0.481; Exploratory analyses FBAT P-value=0.731 for co-morbid CD, P-value=0.256 for co-morbid MDD, P-value=0.249 for co-morbid BD More...	No association was found between ADHD or co-morbidities of A...... No association was found between ADHD or co-morbidities of ADHD and this SNP More...	Non-significant

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
SNAP25	synaptosomal-associated protein, 25kDa	20p12-p11.2	18(13/5/0)

Approved Symbol	Approved Name	Location
SNAP25-AS1	SNAP25 antisense RNA 1	20p12.2

SNPs in LD with rs2423486 (count: 2) View in gBrowse (chr20:10203817..10212212 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs6032826	intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs3787303	intron_variant; nc_transcript_variant	0.827[CEU]; 1.0[CHB]; 1.0[JPT]