ADHDgene Database

SNP Report

Basic Info

Name	rs2206161 dbSNP Ensembl
Location	Chr20:10334969(Fwd)
Variant Alleles	C/T
Ancestral Allele	C
Functional Annotation	intron_variant; nc_transcript_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000421143; ENST00000453544) nc_transcript_variant(ENST00000421143; ENST00000453544) upstream_gene_variant(ENST00000446637)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Kim JW, 2007	T/C	C	Single marker analysis FBAT P-value=0.295; Exploratory analy...... Single marker analysis FBAT P-value=0.295; Exploratory analyses FBAT P-value=0.66 for co-morbid CD, P-value=0.265 for co-morbid MDD, P-value=0.283 for co-morbid BD More...	No association was found between ADHD or co-morbidities of A...... No association was found between ADHD or co-morbidities of ADHD and this SNP More...	Non-significant

SNP related genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
SNAP25	synaptosomal-associated protein, 25kDa	20p12-p11.2	18(13/5/0)

Approved Symbol	Approved Name	Location
RPL23AP6	ribosomal protein L23a pseudogene 6	20p12.2
SNAP25-AS1	SNAP25 antisense RNA 1	20p12.2

SNPs in LD with rs2206161 (count: 4) View in gBrowse (chr20:10334478..10342441 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs6108509	downstream_gene_variant; intron_variant; nc_transcript_variant	0.862[JPT]
rs2423497	downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs4813932	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 0.933[CHD]; 1.0[GIH]; 1.0[JPT]; 0.916[MEX]; 1.0[TSI]
rs2423492	intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 0.967[CHD]; 1.0[GIH]; 1.0[JPT]; 0.957[MEX]; 1.0[TSI]