ADHDgene Database

SNP Report

Basic Info

Name	rs2143340 dbSNP Ensembl
Location	chr6:24659071(Fwd)
Variant Alleles	A/G
Ancestral Allele	A
Functional Annotation	intron_variant; nc_transcript_variant; non_coding_exon_variant.
Consequence to Transcript	intron_variant(ENST00000341060; ENST00000378198; ENST00000478507; ENST00000545995) nc_transcript_variant(ENST00000478285; ENST00000478507) non_coding_exon_variant(ENST00000478285)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Couto JM, 2009	G:A		Single-marker TDT analysis P-value=0.712 Single-marker TDT analysis P-value=0.712	This marker in gene TTRAP was not associated with ADHD This marker in gene TTRAP was not associated with ADHD	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
TDP2	tyrosyl-DNA phosphodiesterase 2	6p22.3-p22.1	1(0/1/0)

SNPs in LD with rs2143340 (count: 4) View in gBrowse (chr6:24651388..24693523 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs7768291	intron_variant; nc_transcript_variant	0.944[CEU]; 1.0[CHB]; 1.0[JPT]; 0.898[YRI]
rs3181244	downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 0.915[JPT]
rs3777665	intron_variant; nc_transcript_variant	0.883[CEU]; 1.0[CHB]
rs3756819	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]